Product overview

• NameMiltefosine
• Short descriptionAkt inhibitor
• Biological descriptionAkt inhibitor. Inhibits T-cell proliferation and HIV-1 cell survival and production. Displays anti-inflammatory and anticancer properties with broad spectrum of fungicidal and antiamoebae activities. Blood brain barrier permeable.
• Biological actionInhibitor
• Purity>98%
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Properties

• Chemical name1-Hexadecylphosphorylcholine
• Molecular Weight407.6
• Chemical structure
• Molecular FormulaC₂₁H₄₆NO₄P
• CAS Number58066-85-6
• PubChem identifier3599
• SMILESCCCCCCCCCCCCCCCCOP(=O)([O-])OCC[N+](C)(C)C

Storing and Using Your Product

• ImportantThis product is for RESEARCH USE ONLY and is not intended for therapeutic or diagnostic use. Not for human or veterinary use.

References for Miltefosine

• Miltefosine suppresses inflammation in a mouse model of inflammatory bowel disease.

  Verhaar AP et al (2013)Inflamm Bowel Dis 19(9) : 1974-82. PubMedID: 23811637

• Akt inhibitors as an HIV-1 infected macrophage-specific anti-viral therapy.

  Chugh P et al (2008)Retrovirology 5 : 11 PubMedID: 18237430

• Miltefosine enhances phagocytosis but decreases nitric oxide production by peritoneal macrophages of C57BL/6 mice.

  Ponte CB et al (2012)Int Immunopharmacol 13(1) : 114-9. PubMedID: 22465961