你好Bio/Fura-2 AM/HB0780/1mg
市场价：
¥2866.50
美元价：
2205.00
产品分类：
酸碱缓冲液
联系Q Q：
3392242852
电话号码：
4000-520-616
电子邮箱：
info@ebiomall.com
商品介绍
Productoverview
- NameFura-2AM
- ShortdescriptionHighaffinity,cellpermeablecalciumindicatorwhichisratiometricandUVlightexcitable
- BIOLOGicaldescription
Highaffinity,cellpermeablecalciumindicatorwhichisratiometricandUVlightexcitable.AMesterderivativeofFura-2.Cannoninvasivelybeloadedintolivecellsbyincubation.Widelyusedforratio-imagingmicroscopyandmeasuresintracellularcalciumelevationsinneuronsandotherexcitablecells.Excitation340/380nm,Emission505nm.
- BiologicalactionDyes&stains
- Purity>95%
- OurproductsinactionSubmitYourCitationNow
Properties
- Chemicalname1-[2-(5-Carboxyoxazol-2-yl)-6-aminobenzofuran-5-oxy]-2-(2"-amino-5"-methyl-phenoxy)ethane-N,N,N",N"-tetraaceticacid,pentaacetoxymethylester
- MolecularWeight1001.9
- Chemicalstructure
![Fura-2 AM [108964-32-5]](images/hellobio/201710/hb0780.png "Fura-2 AM [108964-32-5]")
- MolecularFormulaC44H47N3O24
- CASNumber108964-32-5
- PubChemidentifier3364574
- SMILESCC1=CC(=C(C=C1)N(CC(=O)OCOC(=O)C)CC(=O)OCOC(=O)C)OCCOC2=C(C=C3C(=C2)C=C(O3)C4=NC=C(O4)C(=O)OCOC(=O)C)N(CC(=O)OCOC(=O)C)CC(=O)OCOC(=O)C
- InChiInChI=1S/C44H47N3O24/c1-25-7-8-32(46(16-39(53)65-20-60-26(2)48)17-40(54)66-21-61-27(3)49)35(11-25)58-9-10-59-36-12-31-13-37(43-45-15-38(71-43)44(57)69-24-64-30(6)52)70-34(31)14-33(36)47(18-41(55)67-22-62-28(4)50)19-42(56)68-23-63-29(5)51/h7-8,11-15H,9-10,
- InChiKeyVPSRLGDRGCKUTK-UHFFFAOYSA-N
- MDLnumberMFCD00036976
- AppearanceYellowsolid
StoringandUsingYourProduct
- Storageinstructions-20°C
- SolubilityoverviewSolubleinDMSO(10mM)
- ImportantThisproductisforRESEARCHUSEONLYandisnotintendedfortherapeuticordiagnosticuse.Notforhumanorveterinaryuse.
ReferencesforFura-2AM
CalciumimagingofcorticalneuronsusingFura-2AM.
Barreto-ChangOLetal(2009)JVisExp-23:PubMedID:19229178Effectsoftransmittersandamyloid-betapeptideoncalciumsignalsinratcorticalastrocytes:Fura-2AMmeasurementsandstochasticmodelsimulations.
ToivariEetal(2011)PLoSOne6(3):e17914.PubMedID:21483471Fura-2measurementofcytosolicfreeCa2+inmonolayersandsUSPensionsofvarioustypesofanimalcells.
MalgaroliAetal(1987)JCellBiol105(5):2145-55.PubMedID:3680375
品牌介绍
Hello Bio是由一群经验丰富的科学家和化学家们创立的充满活力的生物企业，总部位于英国布里斯托尔，在美国普林斯顿设有分公司，主旨在于提供质优价廉的生命科学研究工具，主要产品线为小分子化合物，如激动剂、拮抗剂、抑制剂等，部分产品价格甚至低至其他供应商的50%。热销产品线：酶抑制剂和激动剂ROCK inhibitor Y-27632, PKA inhibitor KT 5720 , adenylyl cyclase activator Forskolin, and novel GRK2/3 inhibitor Cmpd101等。 离子通道调节剂NMDA antagonist D-AP5, sodium channel blocker tetrodotoxin citrate, TRP antagonist capsazepine, and GABAA antagonist SR 95531 等。信号通路工具各种信号通路抑制剂、激动剂表观遗传学研究工具potent HDAC inhibitor Trichostatin A, DNA methyltransferase inhibitor 5-aza-2'-deoxycytidine,BET bromodomain inhibitor (+)-JQ1 and potent,selective GLP / G9a HMTase inhibitor BIX 01294 等受体配体novel selective GRK2/3 inhibitor, NMDA antagonist D-AP5, Group I mGlu agonist (S)-3,5-DHPG, and GABAA antagonist SR 95531.等干细胞调节剂ROCK inhibitor Y-27632, SB 431542 DAPT.
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