你好Bio/BrdU（5-溴-2′-脱氧尿苷）/HB0979/250mg
市场价：
¥799.50
美元价：
615.00
产品分类：
酸碱缓冲液
联系Q Q：
3392242852
电话号码：
4000-520-616
电子邮箱：
info@ebiomall.com
商品介绍
Productoverview
- NameBrdU(5-Bromo-2′-deoxyuridine)
- ShortdescriptionThymidineanalog.Widelyusedtoidentifyproliferatingcells.
- BIOLOGicaldescription
ThymidineanalogwhichisincorporatedintoDNAduringDNAreplication(duringS-phaseofcellcycle).
BrdUisusedtoidentifyproliferatingcells. Labelscelllinesandprimarycellculturesinvitroandalsocellsinvivo.
Widelyusedtostudyadultneurogenesis.CanbeusedincombinationwithneuronspecificMarkerssuchasNeuNtoidentifynewlyformedneurons.Frequentlyusedtolabelandfate-mapdividingcellsinneuralstemcellbiology.
- Alternativenames5-BrdU,5-bromo-2"-deoxyuridine,Broxuridine
- BiologicalactionDyes&stains
- Purity>98%
- OurproductsinactionSubmitYourCitationNow
Properties
- Chemicalname5-Bromo-2-deoxyuridine
- MolecularWeight307.1
- Chemicalstructure
![BrdU [59-14-3]](images/hellobio/201710/hb0979.png "BrdU [59-14-3]")
- MolecularFormulaC9H11BrN2O5
- CASNumber59-14-3
- PubChemidentifier6035
- SMILESC1[C@@H]([C@H](O[C@H]1N2C=C(C(=O)NC2=O)Br)CO)O
- SourceSynthetic
- InChiInChI=1S/C9H11BrN2O5/c10-4-2-12(9(16)11-8(4)15)7-1-5(14)6(3-13)17-7/h4,5-7,13-14H,1,3H2,(H,11,15,16)/t5-,6+,7+/m0/s1
- InChiKeyWOVKYSAHUYNSMH-RRKCRQDMSA-N
- MDLnumberMFCD00006529
- AppearanceWhitesolid
StoringandUsingYourProduct
- Storageinstructions-20°C
- SolubilityoverviewSolubleinwater(50mM)andinDMSO(100mM)
- ImportantThisproductisforRESEARCHUSEONLYandisnotintendedfortherapeuticordiagnosticuse.Notforhumanorveterinaryuse.
ReferencesforBrdU(5-Bromo-2′-deoxyuridine)
Pharmacologicalevaluationofintravenousdeliveryof5-bromodeoxyuridinetopatientswithbraintumors.
RussoAetal(1984)CancerRes44(4):1702-5.PubMedID:6704976Neurogenesisintheadulthumanhippocampus.
ErikssonPSetal(1998)NatMed4(11):1313-7.PubMedID:9809557ThedarksideofBrdUinneuralstemcellbiology:detrimentaleffectsoncellcycle,differentiationandsurvival.
LehnerBetal(2011)CellTissueRes345(3):313-28.PubMedID:21837406
品牌介绍
Hello Bio是由一群经验丰富的科学家和化学家们创立的充满活力的生物企业，总部位于英国布里斯托尔，在美国普林斯顿设有分公司，主旨在于提供质优价廉的生命科学研究工具，主要产品线为小分子化合物，如激动剂、拮抗剂、抑制剂等，部分产品价格甚至低至其他供应商的50%。热销产品线：酶抑制剂和激动剂ROCK inhibitor Y-27632, PKA inhibitor KT 5720 , adenylyl cyclase activator Forskolin, and novel GRK2/3 inhibitor Cmpd101等。 离子通道调节剂NMDA antagonist D-AP5, sodium channel blocker tetrodotoxin citrate, TRP antagonist capsazepine, and GABAA antagonist SR 95531 等。信号通路工具各种信号通路抑制剂、激动剂表观遗传学研究工具potent HDAC inhibitor Trichostatin A, DNA methyltransferase inhibitor 5-aza-2'-deoxycytidine,BET bromodomain inhibitor (+)-JQ1 and potent,selective GLP / G9a HMTase inhibitor BIX 01294 等受体配体novel selective GRK2/3 inhibitor, NMDA antagonist D-AP5, Group I mGlu agonist (S)-3,5-DHPG, and GABAA antagonist SR 95531.等干细胞调节剂ROCK inhibitor Y-27632, SB 431542 DAPT.
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