Hello Bio/Mitomycin C/HB4458/5mg
市场价：
¥994.50
美元价：
765.00
产品分类：
酸碱缓冲液
联系Q Q：
3392242852
电话号码：
4000-520-616
电子邮箱：
info@ebiomall.com
商品介绍
Productoverview
- NameMitomycinC
- ShortdescriptionAntibiotic.DNAsynthesisinhibitor.
- BIOLOGicaldescription
Inhibitsproliferationofvariouscelltypes.InhibitsDNAsynthesisbyformingcovalentcrosslinksbetweencomplementaryDNAstrands.
Widelyusedfortreatmentoffeedercelllayers(e.g.forPMEF(primarymouseembryonicfibroblasts)andCD1mouseembryonicfibroblasts(MEFs)andhESCs(humanembryonicstemcells).
Alsoshowsantitumoractivity. - AlternativenamesAmetycine,MMC,NSC26980
- BiologicalactionAntibiotic
- ApplicationsCellCulture
- OurproductsinactionSubmitYourCitationNow
Properties
- Chemicalname[1aS-(1a?,8?,8a?,8b?)]-6-Amino-8-[[(aminocarbonyl)oxy]methyl]-1,1a,2,8,8a,8b-hexahydro-8a-methoxy-5-methylazirino[2",3":3,4]pyrrolo[1,2-a]indole-4,7-dione
- MolecularWeight334.33
- MolecularFormulaC15H18N4O5
- CASNumber50-07-7
- PubChemidentifier5746
- SMILESCC1=C(C(=O)C2=C(C1=O)N3C[C@H]4[C@@H]([C@@]3([C@@H]2COC(=O)N)OC)N4)N
- InChiKeyNWIBSHFKIJFRCO-WUDYKRTCSA-N
- MDLnumberMFCD00078109
- AppearancePurple
StoringandUsingYourProduct
- Storageinstructions+4°C;
- SolubilityoverviewSolubleinDMSO(100mM)andwater(5mM)
- ImportantThisproductisforRESEARCHUSEONLYandisnotintendedfortherapeuticordiagnosticuse.Notforhumanorveterinaryuse.
ReferencesforMitomycinC
MitomycinCasanalternativetoirrADIationtoinhibitthefeederlayergrowthinlong-termcultureassays.
Ponchioetal(2000)Cytotherapy2(4):281-6PubMedID:12042037Isolationandstructureofanintrastrandcross-linkadductofmitomycinCandDNA.
Bizaneketal(1992)Biochemistry31(12):3084-19PubMedID:1554696Isolationandstructureofacovalentcross-linkadductbetweenmitomycinCandDNA.
Tomaszetal(1987)Science235(4793):1204-8PubMedID:3103215
品牌介绍
Hello Bio是由一群经验丰富的科学家和化学家们创立的充满活力的生物企业，总部位于英国布里斯托尔，在美国普林斯顿设有分公司，主旨在于提供质优价廉的生命科学研究工具，主要产品线为小分子化合物，如激动剂、拮抗剂、抑制剂等，部分产品价格甚至低至其他供应商的50%。热销产品线：酶抑制剂和激动剂ROCK inhibitor Y-27632, PKA inhibitor KT 5720 , adenylyl cyclase activator Forskolin, and novel GRK2/3 inhibitor Cmpd101等。 离子通道调节剂NMDA antagonist D-AP5, sodium channel blocker tetrodotoxin citrate, TRP antagonist capsazepine, and GABAA antagonist SR 95531 等。信号通路工具各种信号通路抑制剂、激动剂表观遗传学研究工具potent HDAC inhibitor Trichostatin A, DNA methyltransferase inhibitor 5-aza-2'-deoxycytidine,BET bromodomain inhibitor (+)-JQ1 and potent,selective GLP / G9a HMTase inhibitor BIX 01294 等受体配体novel selective GRK2/3 inhibitor, NMDA antagonist D-AP5, Group I mGlu agonist (S)-3,5-DHPG, and GABAA antagonist SR 95531.等干细胞调节剂ROCK inhibitor Y-27632, SB 431542 DAPT.
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