Hello Bio/Z-VDVAD-FMK/HB1286/5mg
市场价：
¥16068.00
美元价：
12360.00
产品分类：
酸碱缓冲液
联系Q Q：
3392242852
电话号码：
4000-520-616
电子邮箱：
info@ebiomall.com
商品介绍
Productoverview
- NameZ-VDVAD-FMK
- ShortdescriptionIrreversIBLecaspase2inhibitor
- BIOLOGicaldescriptionIrreversiblecaspase2inhibitor.Significantlyreducescelldetachment,caspase-2and-3activity,DNAladders,andproteolyticcleavageofPARP.Displaysinhibitoryapoptoticactions.
- BiologicalactionInhibitor
- OurproductsinactionSubmitYourCitationNow
Properties
- ChemicalnameBenzyloxycarbonyl-Val-Asp(OMe)-Val-Ala-Asp(OMe)-fluoromethylketone
- MolecularWeight695.74
- MolecularFormulaC32H46FN5O11
StoringandUsingYourProduct
- Storageinstructions-20°C
- SolubilityoverviewsolubleinDMSO(13.791mg/ml)
- ImportantThisproductisforRESEARCHUSEONLYandisnotintendedfortherapeuticordiagnosticuse.Notforhumanorveterinaryuse.
ReferencesforZ-VDVAD-FMK
DoxorubicintreatmentactivatesaZ-VAD-sensitivecaspase,whichcausesdeltapsimloss,caspase-9activity,andapoptosisinJurkatcells.
GamenSetal(2000)ExpCellRes258(1):223-35.PubMedID:10912804Caspaseinhibitorsattenuateoxyhemoglobin-inducedapoptosisinendothelialcells.
MeguroTetal(2001)Stroke32(2):561-6.PubMedID:11157197Upstreamcontrolofapoptosisbycaspase-2inserum-deprivedprimaryneurons.
ChauvierDetal(2005)Apoptosis10(6):1243-59.PubMedID:16215683
品牌介绍
Hello Bio是由一群经验丰富的科学家和化学家们创立的充满活力的生物企业，总部位于英国布里斯托尔，在美国普林斯顿设有分公司，主旨在于提供质优价廉的生命科学研究工具，主要产品线为小分子化合物，如激动剂、拮抗剂、抑制剂等，部分产品价格甚至低至其他供应商的50%。热销产品线：酶抑制剂和激动剂ROCK inhibitor Y-27632, PKA inhibitor KT 5720 , adenylyl cyclase activator Forskolin, and novel GRK2/3 inhibitor Cmpd101等。 离子通道调节剂NMDA antagonist D-AP5, sodium channel blocker tetrodotoxin citrate, TRP antagonist capsazepine, and GABAA antagonist SR 95531 等。信号通路工具各种信号通路抑制剂、激动剂表观遗传学研究工具potent HDAC inhibitor Trichostatin A, DNA methyltransferase inhibitor 5-aza-2'-deoxycytidine,BET bromodomain inhibitor (+)-JQ1 and potent,selective GLP / G9a HMTase inhibitor BIX 01294 等受体配体novel selective GRK2/3 inhibitor, NMDA antagonist D-AP5, Group I mGlu agonist (S)-3,5-DHPG, and GABAA antagonist SR 95531.等干细胞调节剂ROCK inhibitor Y-27632, SB 431542 DAPT.
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