Hello Bio/Zebularine/HB1378/
市场价：
¥585.00
美元价：
450.00
产品分类：
酸碱缓冲液
联系Q Q：
3392242852
电话号码：
4000-520-616
电子邮箱：
info@ebiomall.com
商品介绍
Productoverview
- NameZebularine
- ShortdescriptionDNAmethyltransferaseinhibitor.InducescardiomyocytedifferentiationinMSCs.
- BIOLOGicaldescriptionDNAmethyltransferaseinhibitor.StABIlisesp53incolorectalcancercellsandcausesp53-dependentERstressandautophagy.Alsoinhibitscytidinedeaminaseandinfluencesembryonicstemcelldifferentiation.Showsanti-proliferativeandanti-canceractions.
- Alternativenames1-(β-D-Ribofuranosyl)-1,2-dihydropyrimidin-2-one;2-Pyrimidone-1-β-D-riboside;NSC309132;Zeb
- BiologicalactionInhibitor
- Purity>99%
- OurproductsinactionSubmitYourCitationNow
Properties
- Chemicalname1-β-D-Ribofuranosyl-2(1H)-pyrimidinone
- MolecularWeight228.2
- Chemicalstructure
![Zebularine [654065]](images/hellobio/201710/hb1378.png "Zebularine [654065]")
- MolecularFormulaC9H12N2O5
- CASNumber654065
StoringandUsingYourProduct
- Storageinstructionsroomtemperature(desiccate)
- Solubilityoverviewsolubleinwater(100mM)orDMSO(100mM)
- ImportantThisproductisforRESEARCHUSEONLYandisnotintendedfortherapeuticordiagnosticuse.Notforhumanorveterinaryuse.
ReferencesforZebularine
ZebularineinhibitstumOrigenesisandstemnessofcolorectalcancerviap53-dependentendoplasmicreticulumstress.
YangPMetal(2013)SciRep3:3219PubMedID:24225777ZebularineregulatesearlystagesofmESCdifferentiation:effectoncardiaccommitment.
HorrilloAetal(2013)CellDeathDis4:e570.PubMedID:23559004Potentinhibitorsforthedeaminationofcytosinearabinosideand5-aza-2"-deoxycytidinebyhumancytidinedeaminase.
Lalibertã?Jetal(1992)CancerChemotherPharmacol30(1):7-11.PubMedID:1375134
品牌介绍
Hello Bio是由一群经验丰富的科学家和化学家们创立的充满活力的生物企业，总部位于英国布里斯托尔，在美国普林斯顿设有分公司，主旨在于提供质优价廉的生命科学研究工具，主要产品线为小分子化合物，如激动剂、拮抗剂、抑制剂等，部分产品价格甚至低至其他供应商的50%。热销产品线：酶抑制剂和激动剂ROCK inhibitor Y-27632, PKA inhibitor KT 5720 , adenylyl cyclase activator Forskolin, and novel GRK2/3 inhibitor Cmpd101等。 离子通道调节剂NMDA antagonist D-AP5, sodium channel blocker tetrodotoxin citrate, TRP antagonist capsazepine, and GABAA antagonist SR 95531 等。信号通路工具各种信号通路抑制剂、激动剂表观遗传学研究工具potent HDAC inhibitor Trichostatin A, DNA methyltransferase inhibitor 5-aza-2'-deoxycytidine,BET bromodomain inhibitor (+)-JQ1 and potent,selective GLP / G9a HMTase inhibitor BIX 01294 等受体配体novel selective GRK2/3 inhibitor, NMDA antagonist D-AP5, Group I mGlu agonist (S)-3,5-DHPG, and GABAA antagonist SR 95531.等干细胞调节剂ROCK inhibitor Y-27632, SB 431542 DAPT.
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