Hello Bio/(-)-Xestospongin C/HB1241/50μg
市场价：
¥10939.50
美元价：
8415.00
产品分类：
酸碱缓冲液
联系Q Q：
3392242852
电话号码：
4000-520-616
电子邮箱：
info@ebiomall.com
商品介绍
Productoverview
- Name(-)-XestosponginC
- ShortdescriptionPotentIP3receptorinhibitor
- BIOLOGicaldescriptionPotentIP3receptorinhibitor.InhibitsP3-mediatedCa2+release(IC50=358nM).SelectiveforIP3receptorsoverryanodinereceptors.Inhibitssarcoplasmic/endoplasmicreticulumCa2+ATPaseSERCApump.
- BiologicalactionInhibitor
- OurproductsinactionSubmitYourCitationNow
Properties
- Chemicalname(1R,4aR,11R,12aS,13S,16aS,23R,24aS)-Eicosahydro-5H,17H-1,23:11,13-diethano-2H,14H-[1,11]dioxacycloeicosino[2,3-b:12,13-b"]dipyridine
- MolecularWeight446.71
- Chemicalstructure
![(-)-Xestospongin C [88903-69-9]](images/hellobio/201710/hb1241.png "(-)-Xestospongin C [88903-69-9]")
- MolecularFormulaC28H50N2O2
- CASNumber88903-69-9
StoringandUsingYourProduct
- Storageinstructions-20°C(desiccate)
- SolubilityoverviewsolubleinDMSO(2mM)orethanol(2mM)
- ImportantThisproductisforRESEARCHUSEONLYandisnotintendedfortherapeuticordiagnosticuse.Notforhumanorveterinaryuse.
Referencesfor(-)-XestosponginC
Xestospongins:potentmembranepermeableblockersoftheinositol1,4,5-trisphosphatereceptor.
GafniJetal(1997)Neuron19(3):723-33.PubMedID:9331361XestosponginCisapotentinhibitorofSERCAatavertebratesynapse.
CastonguayAetal(2002)CellCalcium32(1):39-47.PubMedID:12127061XestosponginCisanequallypotentinhibitoroftheinositol1,4,5-trisphosphatereceptorandtheendoplasmic-reticulumCa(2+)pumps.
DeSmetPetal(1999)CellCalcium26(1-2):9-13.PubMedID:10892566
品牌介绍
Hello Bio是由一群经验丰富的科学家和化学家们创立的充满活力的生物企业，总部位于英国布里斯托尔，在美国普林斯顿设有分公司，主旨在于提供质优价廉的生命科学研究工具，主要产品线为小分子化合物，如激动剂、拮抗剂、抑制剂等，部分产品价格甚至低至其他供应商的50%。热销产品线：酶抑制剂和激动剂ROCK inhibitor Y-27632, PKA inhibitor KT 5720 , adenylyl cyclase activator Forskolin, and novel GRK2/3 inhibitor Cmpd101等。 离子通道调节剂NMDA antagonist D-AP5, sodium channel blocker tetrodotoxin citrate, TRP antagonist capsazepine, and GABAA antagonist SR 95531 等。信号通路工具各种信号通路抑制剂、激动剂表观遗传学研究工具potent HDAC inhibitor Trichostatin A, DNA methyltransferase inhibitor 5-aza-2'-deoxycytidine,BET bromodomain inhibitor (+)-JQ1 and potent,selective GLP / G9a HMTase inhibitor BIX 01294 等受体配体novel selective GRK2/3 inhibitor, NMDA antagonist D-AP5, Group I mGlu agonist (S)-3,5-DHPG, and GABAA antagonist SR 95531.等干细胞调节剂ROCK inhibitor Y-27632, SB 431542 DAPT.
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