Hello Bio/Wortmannin/HB2778/10mg
市场价：
¥7176.00
美元价：
5520.00
产品分类：
酸碱缓冲液
联系Q Q：
3392242852
电话号码：
4000-520-616
电子邮箱：
info@ebiomall.com
商品介绍
Productoverview
- NameWortmannin
- ShortdescriptionPotent,selective,irreversIBLePI3-Kinhibitor
- BIOLOGicaldescriptionPotent,selective,non-compettiveandirreversiblePI3-Kinhibitor(IC50=2-4nM).AlsoinhibitsPI3-KrelatedkinasesandPLK1.Cellpermeable.Showsvarietyofbiologicalactions.
- AlternativenamesSL-2052
- BiologicalactionInhibitor
- OurproductsinactionSubmitYourCitationNow
Properties
- Chemicalname(1S,6bR,9aS,11R,11bR)11-(Acetyloxy)-1,6b,7,8,9a,10,11,11b-octahydro-1-(methoxymethyl)-9a,11b-dimethyl-3H-furo[4,3,2-de]indeno[4,5,-h]-2-h]-2-benzopyran-3,6,9-trione
- MolecularWeight428.44
- MolecularFormulaC23H24O8
- CASNumber19545-26-7
StoringandUsingYourProduct
- Storageinstructions-20°C(desiccate)
- ImportantThisproductisforRESEARCHUSEONLYandisnotintendedfortherapeuticordiagnosticuse.Notforhumanorveterinaryuse.
ReferencesforWortmannin
Wortmanninasauniqueprobeforanintracellularsignallingprotein,phosphoinositide3-kinase.
Uietal(1995)TrendsBiochemSci20(8):303-7PubMedID:7667888Wortmannin,apotentandselectiveinhibitorofphosphatidylinositol-3-kinase.
Powisetal(1994)CancerRes54(9):2419-23PubMedID:8162590Wortmannin,awidelyusedphosphoinositide3-kinaseinhibitor,alsopotentlyinhibitsmammalianpolo-likekinase.
Liuetal(2005)ChemBiol12(1):99-107PubMedID:15664519
品牌介绍
Hello Bio是由一群经验丰富的科学家和化学家们创立的充满活力的生物企业，总部位于英国布里斯托尔，在美国普林斯顿设有分公司，主旨在于提供质优价廉的生命科学研究工具，主要产品线为小分子化合物，如激动剂、拮抗剂、抑制剂等，部分产品价格甚至低至其他供应商的50%。热销产品线：酶抑制剂和激动剂ROCK inhibitor Y-27632, PKA inhibitor KT 5720 , adenylyl cyclase activator Forskolin, and novel GRK2/3 inhibitor Cmpd101等。 离子通道调节剂NMDA antagonist D-AP5, sodium channel blocker tetrodotoxin citrate, TRP antagonist capsazepine, and GABAA antagonist SR 95531 等。信号通路工具各种信号通路抑制剂、激动剂表观遗传学研究工具potent HDAC inhibitor Trichostatin A, DNA methyltransferase inhibitor 5-aza-2'-deoxycytidine,BET bromodomain inhibitor (+)-JQ1 and potent,selective GLP / G9a HMTase inhibitor BIX 01294 等受体配体novel selective GRK2/3 inhibitor, NMDA antagonist D-AP5, Group I mGlu agonist (S)-3,5-DHPG, and GABAA antagonist SR 95531.等干细胞调节剂ROCK inhibitor Y-27632, SB 431542 DAPT.
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