你好Bio/Wiskostatin/HB0658/50mg
市场价：
¥11388.00
美元价：
8760.00
产品分类：
酸碱缓冲液
联系Q Q：
3392242852
电话号码：
4000-520-616
电子邮箱：
info@ebiomall.com
商品介绍
Productoverview
- NameWiskostatin
- ShortdescriptionPotent,selectiveN-WASPinhibitor
- BIOLOGicaldescriptionPotentandselectiveneuralWiskott-Aldrichsyndromeprotein(N-WASP)inhibitorthatinteractswithGTPase-bindingdomain.InhibitsArp2/3complexactivation.DecreasescellularATPlevelsandinhibitscytokinesisbutnotmitosis.Acarbazolederivative.
- BiologicalactionInhibitor
- Purity>99%
- OurproductsinactionSubmitYourCitationNow
Properties
- Chemicalname3,6-Dibromo-α-[(dimethylamino)methyl]-9H-cabazole-9-ethanol
- MolecularWeight426.15
- Chemicalstructure
![Wiskostatin [253449-04-6]](images/hellobio/201710/hb0658.png "Wiskostatin [253449-04-6]")
- MolecularFormulaC17H18Br2N2O
- CASNumber253449-04-6
StoringandUsingYourProduct
- Storageinstructions+4°C
- SolubilityoverviewsolubleinDMSO(100mM)
- ImportantThisproductisforRESEARCHUSEONLYandisnotintendedfortherapeuticordiagnosticuse.Notforhumanorveterinaryuse.
ReferencesforWiskostatin
ChemicalinhibitionofN-WASPbystABIlizationofanativeautoinhibitedconformation.
PetersonJRetal(2004)NatStructMolBiol11(8):747-55.PubMedID:15235593InhibitionofcytokinesisbywiskostatindoesnotrelyonN-WASP/Arp2/3complexpathway.
BompardGetal(2008)BMCCellBiol9:42PubMedID:18667055N-WASPinhibitorwiskostatinnonselectivelyperturbsmembranetransportbydecreasingcellularATPlevels.
GuerrieroCJetal(2007)AmJPhysiolCellPhysiol292(4):C1562-6.PubMedID:17092993
品牌介绍
Hello Bio是由一群经验丰富的科学家和化学家们创立的充满活力的生物企业，总部位于英国布里斯托尔，在美国普林斯顿设有分公司，主旨在于提供质优价廉的生命科学研究工具，主要产品线为小分子化合物，如激动剂、拮抗剂、抑制剂等，部分产品价格甚至低至其他供应商的50%。热销产品线：酶抑制剂和激动剂ROCK inhibitor Y-27632, PKA inhibitor KT 5720 , adenylyl cyclase activator Forskolin, and novel GRK2/3 inhibitor Cmpd101等。 离子通道调节剂NMDA antagonist D-AP5, sodium channel blocker tetrodotoxin citrate, TRP antagonist capsazepine, and GABAA antagonist SR 95531 等。信号通路工具各种信号通路抑制剂、激动剂表观遗传学研究工具potent HDAC inhibitor Trichostatin A, DNA methyltransferase inhibitor 5-aza-2'-deoxycytidine,BET bromodomain inhibitor (+)-JQ1 and potent,selective GLP / G9a HMTase inhibitor BIX 01294 等受体配体novel selective GRK2/3 inhibitor, NMDA antagonist D-AP5, Group I mGlu agonist (S)-3,5-DHPG, and GABAA antagonist SR 95531.等干细胞调节剂ROCK inhibitor Y-27632, SB 431542 DAPT.
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