Hello Bio/UNC 0646/HB1423/10mg
市场价：
¥2847.00
美元价：
2190.00
产品分类：
酸碱缓冲液
联系Q Q：
3392242852
电话号码：
4000-520-616
电子邮箱：
info@ebiomall.com
商品介绍
Productoverview
- NameUNC0646
- ShortdescriptionPotent,selectiveG9a/GLPHMTaseinhibitor
- BIOLOGicaldescriptionPotentandselectiveG9aandG9a-likeprotein(GLP)histonelysinemethyltransferase(HMTase)inhibitor(IC50valuesare6and<15=""nm=""respectively).=""selective=""for=""g9a=""and=""glp=""over=""other="">
- AlternativenamesCompound6
- BiologicalactionInhibitor
- Purity>99%
- OurproductsinactionSubmitYourCitationNow
Properties
- ChemicalnameN-(1-Cyclohexyl-4-piperidinyl)-2-[hexahydro-4-(1-methylethyl)-1H-1,4-diazepin-1-yl]-6-methoxy-7-[3-(1-piperidinyl)propoxy]-4-quinazolinamine
- MolecularWeight621.9
- Chemicalstructure
![UNC 0646 [1320288-17-2]](images/hellobio/201710/hb1423.png "UNC 0646 [1320288-17-2]")
- MolecularFormulaC36H59N7O2
- CASNumber1320288-17-2
StoringandUsingYourProduct
- Storageinstructions+4°C
- SolubilityoverviewsolubleinDMSO(100mM)orethanol(100mM)
- ImportantThisproductisforRESEARCHUSEONLYandisnotintendedfortherapeuticordiagnosticuse.Notforhumanorveterinaryuse.
ReferencesforUNC0646
OptimizationofcellularactivityofG9ainhibitors7-aminoalkoxy-quinazolines.
LiuFetal(2011)JMedChem54(17):6139-50.PubMedID:21780790G9afunctionsasamolecularscaffoldforassemblyoftranscriptionalcoactivatorsonasubsetofglucocorticoidreceptortargetgenes.
BittencourtDetal(2012)ProcNatlAcadSciUSA109(48):19673-8.PubMedID:23151507
品牌介绍
Hello Bio是由一群经验丰富的科学家和化学家们创立的充满活力的生物企业，总部位于英国布里斯托尔，在美国普林斯顿设有分公司，主旨在于提供质优价廉的生命科学研究工具，主要产品线为小分子化合物，如激动剂、拮抗剂、抑制剂等，部分产品价格甚至低至其他供应商的50%。热销产品线：酶抑制剂和激动剂ROCK inhibitor Y-27632, PKA inhibitor KT 5720 , adenylyl cyclase activator Forskolin, and novel GRK2/3 inhibitor Cmpd101等。 离子通道调节剂NMDA antagonist D-AP5, sodium channel blocker tetrodotoxin citrate, TRP antagonist capsazepine, and GABAA antagonist SR 95531 等。信号通路工具各种信号通路抑制剂、激动剂表观遗传学研究工具potent HDAC inhibitor Trichostatin A, DNA methyltransferase inhibitor 5-aza-2'-deoxycytidine,BET bromodomain inhibitor (+)-JQ1 and potent,selective GLP / G9a HMTase inhibitor BIX 01294 等受体配体novel selective GRK2/3 inhibitor, NMDA antagonist D-AP5, Group I mGlu agonist (S)-3,5-DHPG, and GABAA antagonist SR 95531.等干细胞调节剂ROCK inhibitor Y-27632, SB 431542 DAPT.
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