Hello Bio/Torcetrapib/HB0879/50mg
市场价:
¥10764.00
美元价:
8280.00
产品分类:
酸碱缓冲液
联系Q Q:
3392242852
电话号码:
4000-520-616
电子邮箱:
info@ebiomall.com
商品介绍
Productoverview
- NameTorcetrapib
- ShortdescriptionCholesterylestertransferproteininhibitor
- BIOLOGicaldescriptionCholesterylestertransferprotein(CETP)inhibitor.RaisesHDLindyslipidemia,improvesglucosehomeostasisandinsulinresistance.Inhibitsvasodilationandincreasesaldosteronetoshowhypertensiveactions.
- BiologicalactionInhibitor
- Purity>99%
- OurproductsinactionSubmitYourCitationNow
Properties
- Chemicalname(2R,4S)-4-[[[3,5-bis(Trifluoromethyl)phenyl]methyl](methoxycarbonyl)amino]-2-ethyl-6-(trifluoromethyl)-1,2,3,4-tetrahydroquinoline-1-carboxylicacidethylester
- MolecularWeight600.47
- Chemicalstructure
- MolecularFormulaC26H25F9N2O4
- CASNumber262352-17-0
StoringandUsingYourProduct
- Storageinstructionsroomtemperature
- SolubilityoverviewsolubleinDMSO(50mM)
- ImportantThisproductisforRESEARCHUSEONLYandisnotintendedfortherapeuticordiagnosticuse.Notforhumanorveterinaryuse.
ReferencesforTorcetrapib
Torcetrapibproducesendothelialdysfunctionindependentofcholesterylestertransferproteininhibition.
ConnellyMAetal(2010)JCardiovascPharmacol55(5):459-68.PubMedID:20051879RaisingHDLwithCETPinhibitortorcetrapibimprovesglucosehomeostasisindyslipidemicandinsulinresistanthamsters.
BriandFetal(2014)Atherosclerosis233(2):359-62.PubMedID:24530763UpregulatingreversecholesteroltransportwithcholesterylestertransferproteininhibitionrequirescombinationwiththeLDL-loweringdrugberberineindyslipidemichamsters.
BriandFetal(2013)ArteriosclerThrombVascBiol33(1):13-23.PubMedID:23139291
品牌介绍
Hello Bio是由一群经验丰富的科学家和化学家们创立的充满活力的生物企业,总部位于英国布里斯托尔,在美国普林斯顿设有分公司,主旨在于提供质优价廉的生命科学研究工具,主要产品线为小分子化合物,如激动剂、拮抗剂、抑制剂等,部分产品价格甚至低至其他供应商的50%。热销产品线:酶抑制剂和激动剂ROCK inhibitor Y-27632, PKA inhibitor KT 5720 , adenylyl cyclase activator Forskolin, and novel GRK2/3 inhibitor Cmpd101等。 离子通道调节剂NMDA antagonist D-AP5, sodium channel blocker tetrodotoxin citrate, TRP antagonist capsazepine, and GABAA antagonist SR 95531 等。信号通路工具各种信号通路抑制剂、激动剂表观遗传学研究工具potent HDAC inhibitor Trichostatin A, DNA methyltransferase inhibitor 5-aza-2'-deoxycytidine,BET bromodomain inhibitor (+)-JQ1 and potent,selective GLP / G9a HMTase inhibitor BIX 01294 等受体配体novel selective GRK2/3 inhibitor, NMDA antagonist D-AP5, Group I mGlu agonist (S)-3,5-DHPG, and GABAA antagonist SR 95531.等干细胞调节剂ROCK inhibitor Y-27632, SB 431542 DAPT.
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