Hello Bio/Tautomycin/HB0603/100μg
市场价：
¥20611.50
美元价：
15855.00
产品分类：
酸碱缓冲液
联系Q Q：
3392242852
电话号码：
4000-520-616
电子邮箱：
info@ebiomall.com
商品介绍
Productoverview
- NameTautomycin
- ShortdescriptionPotent,selectivePP1/PP2Ainhibitor
- BIOLOGicaldescriptionPotentandselectiveproteinphosphatase1(PP1)and2A(PP2A)inhibitor(IC50valuesare0.58and15nMrespectively).ActivatesRaf-1pathwayandinhibitsGSK-3β.Displaysantitumor,antibioticandantifungalproperties.
- BiologicalactionInhibitor
- Purity>90%
- OurproductsinactionSubmitYourCitationNow
Properties
- MolecularWeight766.95
- MolecularFormulaC41H66O13
- CASNumber109946-35-2
- PubChemidentifier440646
- SMILESC[C@@H]1CC[C@@]2(CC[C@@H]([C@@H](O2)[C@H](C)CC[C@@H]([C@H](C)C(=O)C[C@H]([C@H]([C@@H](C(C)C)OC(=O)C[C@H](C3=C(C(=O)OC3=O)C)O)OC)O)O)C)O[C@H]1CC[C@H](C)C(=O)C
StoringandUsingYourProduct
- Solubilityoverviewsolubleinethanolormethanol
- ImportantThisproductisforRESEARCHUSEONLYandisnotintendedfortherapeuticordiagnosticuse.Notforhumanorveterinaryuse.
ReferencesforTautomycin
TautomycinsuppressesgrowthandneuroendocrinehormoneMarkersincarcinoidcellsthroughactivationoftheRaf-1pathway.
PinchotSNetal(2009)AmJSurg197(3):313-9.PubMedID:19245907FunctionalcharacterizationofttmMunveilsnewtautomycinanalogsandinsightintotautomycinbiosynthesisandactivity.
JuJetal(2009)OrgLett11(7):1639-42.PubMedID:19281218Tautomycetinandtautomycinsuppressthegrowthofmedullarythyroidcancercellsviainhibitionofglycogensynthasekinase-3beta.
AdlerJTetal(2009)MolCancerTher8(4):914-20.PubMedID:19372564
品牌介绍
Hello Bio是由一群经验丰富的科学家和化学家们创立的充满活力的生物企业，总部位于英国布里斯托尔，在美国普林斯顿设有分公司，主旨在于提供质优价廉的生命科学研究工具，主要产品线为小分子化合物，如激动剂、拮抗剂、抑制剂等，部分产品价格甚至低至其他供应商的50%。热销产品线：酶抑制剂和激动剂ROCK inhibitor Y-27632, PKA inhibitor KT 5720 , adenylyl cyclase activator Forskolin, and novel GRK2/3 inhibitor Cmpd101等。 离子通道调节剂NMDA antagonist D-AP5, sodium channel blocker tetrodotoxin citrate, TRP antagonist capsazepine, and GABAA antagonist SR 95531 等。信号通路工具各种信号通路抑制剂、激动剂表观遗传学研究工具potent HDAC inhibitor Trichostatin A, DNA methyltransferase inhibitor 5-aza-2'-deoxycytidine,BET bromodomain inhibitor (+)-JQ1 and potent,selective GLP / G9a HMTase inhibitor BIX 01294 等受体配体novel selective GRK2/3 inhibitor, NMDA antagonist D-AP5, Group I mGlu agonist (S)-3,5-DHPG, and GABAA antagonist SR 95531.等干细胞调节剂ROCK inhibitor Y-27632, SB 431542 DAPT.
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