Hello Bio/Tautomycin/HB0603/50μg
市场价：
¥13767.00
美元价：
10590.00
产品分类：
酸碱缓冲液
联系Q Q：
3392242852
电话号码：
4000-520-616
电子邮箱：
info@ebiomall.com
商品介绍
Product overview
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NameTautomycin
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Short descriptionPotent, selective PP1 / PP2A inhibitor
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Biological descriptionPotent and selective protein phosphatase 1 (PP1) and 2A (PP2A) inhibitor (IC50 values are 0.58 and 15 nM respectively). Activates Raf-1 pathway and inhibits GSK-3β. Displays antitumor, antibiotic and antifungal properties.
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Biological actionInhibitor
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Purity>90%
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Our products in actionSubmit Your Citation Now
Properties
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Molecular Weight766.95
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Molecular FormulaC41H66O13
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CAS Number109946-35-2
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PubChem identifier440646
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SMILESC[C@@H]1CC[C@@]2(CC[C@@H]([C@@H](O2)[C@H](C)CC[C@@H]([C@H](C)C(=O)C[C@H]([C@H]([C@@H](C(C)C)OC(=O)C[C@H](C3=C(C(=O)OC3=O)C)O)OC)O)O)C)O[C@H]1CC[C@H](C)C(=O)C
Storing and Using Your Product
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Solubility overviewsoluble in ethanol or methanol
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ImportantThis product is for RESEARCH USE ONLY and is not intended for therapeutic or diagnostic use. Not for human or veterinary use.
References for Tautomycin
Tautomycin suppresses growth and neuroendocrine hormone markers in carcinoid cells through activation of the Raf-1 pathway.
Pinchot SN et al (2009) Am J Surg 197(3) : 313-9.PubMedID: 19245907Functional characterization of ttmM unveils new tautomycin analogs and insight into tautomycin biosynthesis and activity.
Ju J et al (2009) Org Lett 11(7) : 1639-42.PubMedID: 19281218Tautomycetin and tautomycin suppress the growth of medullary thyroid cancer cells via inhibition of glycogen synthase kinase-3beta.
Adler JT et al (2009) Mol Cancer Ther 8(4) : 914-20.PubMedID: 19372564
品牌介绍
Hello Bio是由一群经验丰富的科学家和化学家们创立的充满活力的生物企业，总部位于英国布里斯托尔，在美国普林斯顿设有分公司，主旨在于提供质优价廉的生命科学研究工具，主要产品线为小分子化合物，如激动剂、拮抗剂、抑制剂等，部分产品价格甚至低至其他供应商的50%。热销产品线：酶抑制剂和激动剂ROCK inhibitor Y-27632, PKA inhibitor KT 5720 , adenylyl cyclase activator Forskolin, and novel GRK2/3 inhibitor Cmpd101等。 离子通道调节剂NMDA antagonist D-AP5, sodium channel blocker tetrodotoxin citrate, TRP antagonist capsazepine, and GABAA antagonist SR 95531 等。信号通路工具各种信号通路抑制剂、激动剂表观遗传学研究工具potent HDAC inhibitor Trichostatin A, DNA methyltransferase inhibitor 5-aza-2'-deoxycytidine,BET bromodomain inhibitor (+)-JQ1 and potent,selective GLP / G9a HMTase inhibitor BIX 01294 等受体配体novel selective GRK2/3 inhibitor, NMDA antagonist D-AP5, Group I mGlu agonist (S)-3,5-DHPG, and GABAA antagonist SR 95531.等干细胞调节剂ROCK inhibitor Y-27632, SB 431542 DAPT.
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