Hello Bio/Tamoxifen Citrate/HB0602/500mg
市场价：
¥819.00
美元价：
630.00
产品分类：
酸碱缓冲液
联系Q Q：
3392242852
电话号码：
4000-520-616
电子邮箱：
info@ebiomall.com
商品介绍
Productoverview
- NameTamoxifenCitrate
- ShortdescriptionEstrogenreceptorantagoNIST/partialagonist
- BIOLOGicaldescriptionEstrogenreceptorantagonistandalsopartialagonist.AlsopotentchloridechannelHSV-1inhibitor.Bloodbrainbarrierpermeable.Inhibitstumorgrowthandinducesapoptosisinbreastcancercells.Selectivelyinhibitssterolbiosynthesis(IC50=1000nM).Showsneuroprotectivepotential.
- BiologicalactionAntagonist
- Purity>99%
- OurproductsinactionSubmitYourCitationNow
Properties
- MolecularWeight563.7
- Chemicalstructure
![Tamoxifen Citrate [54965-24-1]](images/hellobio/201710/hb0602.png "Tamoxifen Citrate [54965-24-1]")
- MolecularFormulaC32H37NO8
- CASNumber54965-24-1
- PubChemidentifier2733525
- SMILESCCC(=C(C1=CC=CC=C1)C2=CC=C(C=C2)OCCN(C)C)C3=CC=CC=C3.C(C(=O)O)C(CC(=O)O)(C(=O)O)O
StoringandUsingYourProduct
- Storageinstructions+4°C
- SolubilityoverviewsolubleinDimethylsulfoxide(100mM),methanol(50mg/ml,gentlewarming)orethanol(10mg/ml,sonication)
- ImportantThisproductisforRESEARCHUSEONLYandisnotintendedfortherapeuticordiagnosticuse.Notforhumanorveterinaryuse.
ReferencesforTamoxifenCitrate
TamoxifeninhibitsinwardrectifierK+2.xfamilyofinwardrectifierchannelsbyinterferingwithphosphatidylinositol4,5-bisphosphate-channelinteractions.
Ponce-BalbuenaDetal(2009)JPharmacolExpTher331(2):563-73.PubMedID:19654266BoththeimmunosuppressantSR31747andtheantiestrogentamoxifenbindtoanemopamil-insensitivesiteofmammalianDelta8-Delta7sterolisomerase.
PaulRetal(1998)JPharmacolExpTher285(3):1296-302.PubMedID:9618436Growthinhibitionofestrogenreceptor-positiveandaromatase-positivehumanbreastcancercellsinmonolayerandspheroidculturesbyletrozole,anastrozole,andtamoxifen.
KijimaIetal(2005)JSteroidBiochemMolBiol97(4):360-8.PubMedID:16263272Inhibitionofherpessimplexvirustype1entrybychloridechannelinhibitorstamoxifenandNPPB.
ZhengKetal(2014)BiochemBiophysResCommun446(4):990-6.PubMedID:24657267
品牌介绍
Hello Bio是由一群经验丰富的科学家和化学家们创立的充满活力的生物企业，总部位于英国布里斯托尔，在美国普林斯顿设有分公司，主旨在于提供质优价廉的生命科学研究工具，主要产品线为小分子化合物，如激动剂、拮抗剂、抑制剂等，部分产品价格甚至低至其他供应商的50%。热销产品线：酶抑制剂和激动剂ROCK inhibitor Y-27632, PKA inhibitor KT 5720 , adenylyl cyclase activator Forskolin, and novel GRK2/3 inhibitor Cmpd101等。 离子通道调节剂NMDA antagonist D-AP5, sodium channel blocker tetrodotoxin citrate, TRP antagonist capsazepine, and GABAA antagonist SR 95531 等。信号通路工具各种信号通路抑制剂、激动剂表观遗传学研究工具potent HDAC inhibitor Trichostatin A, DNA methyltransferase inhibitor 5-aza-2'-deoxycytidine,BET bromodomain inhibitor (+)-JQ1 and potent,selective GLP / G9a HMTase inhibitor BIX 01294 等受体配体novel selective GRK2/3 inhibitor, NMDA antagonist D-AP5, Group I mGlu agonist (S)-3,5-DHPG, and GABAA antagonist SR 95531.等干细胞调节剂ROCK inhibitor Y-27632, SB 431542 DAPT.
联络我们
