你好Bio/STO-609醋酸盐/HB0593/10mg
市场价：
¥4212.00
美元价：
3240.00
产品分类：
酸碱缓冲液
联系Q Q：
3392242852
电话号码：
4000-520-616
电子邮箱：
info@ebiomall.com
商品介绍
Productoverview
- NameSTO-609acetate
- ShortdescriptionPotent,competitive,selectiveCaM-KKinhibitor
- BIOLOGicaldescriptionPotent,competitive,selectiveCaM-KKinhibitorinhibitor(Kivaluesare80and15ng/mlforCaM-KKαandCaM-KKβrespectively).Cell-permeable.Showspotentialanti-osteoporosisactions.
- BiologicalactionInhibitor
- Purity>98%
- OurproductsinactionSubmitYourCitationNow
Properties
- Chemicalname7-Oxo-7H-benzimidazo[2,1-a]benz[de]isoquinoline-3-carboxylicacidacetate
- MolecularWeight374.35
- Chemicalstructure
![STO-609 acetate [1173022-21-3]](images/hellobio/201710/hb0593.png "STO-609 acetate [1173022-21-3]")
- MolecularFormulaC19H10N2O3.C2H4O2
- CASNumber1173022-21-3
StoringandUsingYourProduct
- Storageinstructionsroomtemperature(desiccate)
- SolubilityoverviewsolubleinNaOH(aq)(45mM)orDMSO(10mM)
- ImportantThisproductisforRESEARCHUSEONLYandisnotintendedfortherapeuticordiagnosticuse.Notforhumanorveterinaryuse.
ReferencesforSTO-609acetate
STO-609,aspecificinhibitoroftheCa(2+)/calmodulin-dependentproteinkinasekinase.
TokumitsuHetal(2002)JBiolChem277(18):15813-8.PubMedID:11867640Activationofthearylhydrocarbonreceptorbythecalcium/calmodulin-dependentproteinkinasekinaseinhibitor7-oxo-7H-benzimidazo[2,1-a]benz[de]isoquinoline-3-carboxylicacid(STO-609).
MonteiroPetal(2008)DrugMetabDispos36(12):2556-63.PubMedID:18755850InhibitionofCa2+/calmodulin-dependentproteinkinasekinase2stimulatesosteoblastformationandinhibitsosteoclastdifferentiation.
CaryRLetal(2013)JBoneMinerRes28(7):1599-610.PubMedID:23408651
品牌介绍
Hello Bio是由一群经验丰富的科学家和化学家们创立的充满活力的生物企业，总部位于英国布里斯托尔，在美国普林斯顿设有分公司，主旨在于提供质优价廉的生命科学研究工具，主要产品线为小分子化合物，如激动剂、拮抗剂、抑制剂等，部分产品价格甚至低至其他供应商的50%。热销产品线：酶抑制剂和激动剂ROCK inhibitor Y-27632, PKA inhibitor KT 5720 , adenylyl cyclase activator Forskolin, and novel GRK2/3 inhibitor Cmpd101等。 离子通道调节剂NMDA antagonist D-AP5, sodium channel blocker tetrodotoxin citrate, TRP antagonist capsazepine, and GABAA antagonist SR 95531 等。信号通路工具各种信号通路抑制剂、激动剂表观遗传学研究工具potent HDAC inhibitor Trichostatin A, DNA methyltransferase inhibitor 5-aza-2'-deoxycytidine,BET bromodomain inhibitor (+)-JQ1 and potent,selective GLP / G9a HMTase inhibitor BIX 01294 等受体配体novel selective GRK2/3 inhibitor, NMDA antagonist D-AP5, Group I mGlu agonist (S)-3,5-DHPG, and GABAA antagonist SR 95531.等干细胞调节剂ROCK inhibitor Y-27632, SB 431542 DAPT.
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