你好Bio/Staurosporine/HB0590/1mg
市场价：
¥5479.50
美元价：
4215.00
产品分类：
酸碱缓冲液
联系Q Q：
3392242852
电话号码：
4000-520-616
电子邮箱：
info@ebiomall.com
商品介绍
Product overview
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NameStaurosporine
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Short descriptionPotent, non-specific protein kinase inhibitor
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Biological descriptionPotent and non-specific protein kinase inhibitor (IC50 values are 3, 7, 6 and 20 nM at PKC, PKA, p60v-src tyrosine protein kinase and CAMKII respectively). Cell permeable. Induces apoptosis.
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Alternative namesAM-2282, STS
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Biological actionInhibitor
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Purity>99%
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Our products in actionSubmit Your Citation Now
Properties
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Chemical nameAntibiotic AM-2282
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Molecular Weight466.53
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Chemical structure
![Staurosporine [62996-74-1]](images/hellobio/201710/hb0590.png "Staurosporine [62996-74-1]")
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Molecular FormulaC28H26N4O3
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CAS Number62996-74-1
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PubChem identifier44259
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SMILESCC12C(C(CC(O1)N3C4=CC=CC=C4C5=C6C(=C7C8=CC=CC=C8N2C7=C53)CNC6=O)NC)OC
Storing and Using Your Product
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Storage instructions+4°C
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Solubility overviewsoluble in DMSO (25mg/ml) or DMF (25mg/ml)
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ImportantThis product is for RESEARCH USE ONLY and is not intended for therapeutic or diagnostic use. Not for human or veterinary use.
References for Staurosporine
Staurosporine, a potent inhibitor of phospholipid/Ca++dependent protein kinase.
Tamaoki T et al (1986) Biochem Biophys Res Commun 135(2) : 397-402.PubMedID: 3457562Staurosporine: an effective inhibitor for Ca2+/calmodulin-dependent protein kinase II.
Yanagihara N et al (1991) J Neurochem 56(1) : 294-8.PubMedID: 1846174Staurosporine, K-252 and UCN-01: potent but nonspecific inhibitors of protein kinases.
Rüegg UT et al (1989) Trends Pharmacol Sci 10(6) : 218-20.PubMedID: 2672462
品牌介绍
Hello Bio是由一群经验丰富的科学家和化学家们创立的充满活力的生物企业，总部位于英国布里斯托尔，在美国普林斯顿设有分公司，主旨在于提供质优价廉的生命科学研究工具，主要产品线为小分子化合物，如激动剂、拮抗剂、抑制剂等，部分产品价格甚至低至其他供应商的50%。热销产品线：酶抑制剂和激动剂ROCK inhibitor Y-27632, PKA inhibitor KT 5720 , adenylyl cyclase activator Forskolin, and novel GRK2/3 inhibitor Cmpd101等。 离子通道调节剂NMDA antagonist D-AP5, sodium channel blocker tetrodotoxin citrate, TRP antagonist capsazepine, and GABAA antagonist SR 95531 等。信号通路工具各种信号通路抑制剂、激动剂表观遗传学研究工具potent HDAC inhibitor Trichostatin A, DNA methyltransferase inhibitor 5-aza-2'-deoxycytidine,BET bromodomain inhibitor (+)-JQ1 and potent,selective GLP / G9a HMTase inhibitor BIX 01294 等受体配体novel selective GRK2/3 inhibitor, NMDA antagonist D-AP5, Group I mGlu agonist (S)-3,5-DHPG, and GABAA antagonist SR 95531.等干细胞调节剂ROCK inhibitor Y-27632, SB 431542 DAPT.
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