你好生物/丁酸钠/HB1399/50mg
市场价：
¥487.50
美元价：
375.00
产品分类：
酸碱缓冲液
联系Q Q：
3392242852
电话号码：
4000-520-616
电子邮箱：
info@ebiomall.com
商品介绍
Productoverview
- NameSodiumbutyrate
- ShortdescriptionHDACinhibitor.DirectsmESCdifferentiationintohepatocytes.
- BIOLOGicaldescriptionHistonedeacetylase(HDAC)inhibitor(IC50valuesare0.3,0.3and0.4mMforHDAC1,7and2respectively).DoesnotinhibitHDAC6andHDAC10.UpregulatesexpressionofpluripotencygenesiniPSCsanddirectsmESCdifferentiationintohepatocytes.Improvescognitionandshowsanti-Alzheimer"sdiseaseandantidepressantactions.
- AlternativenamesNaB;SB
- BiologicalactionInhibitor
- OurproductsinactionSubmitYourCitationNow
Properties
- ChemicalnameButanoicacidsodiumsalt
- MolecularWeight110.09
- Chemicalstructure
![Sodium butyrate | [156-54-7]](images/hellobio/201710/hb1399.png "Sodium butyrate | [156-54-7]")
- MolecularFormulaC4H7NaO2
- CASNumber156-54-7
StoringandUsingYourProduct
- Storageinstructionsroomtemperature
- Solubilityoverviewsolubleinwater(100mM)
- ImportantThisproductisforRESEARCHUSEONLYandisnotintendedfortherapeuticordiagnosticuse.Notforhumanorveterinaryuse.
ReferencesforSodiumbutyrate
Histonedeacetylaseisatargetofvalproicacid-mediatedcellulardifferentiation.
GurvichNetal(2004)CancerRes64(3):1079-86.PubMedID:14871841Sodiumbutyratefunctionsasanantidepressantandimprovescognitionwithenhancedneurotrophicexpressioninmodelsofmaternaldeprivationandchronicmildstress.
ValvassoriSSetal(2014)CurrNeurovascRes11(4):359-66.PubMedID:25233278Sodiumbutyrateefficientlyconvertsfullyreprogrammedinducedpluripotentstemcellsfrommousepartiallyreprogrammedcells.
KangSJetal(2014)CellReprogram16(5):345-54.PubMedID:25093667SodiumbutyrateimprovesmemoryfunctioninanAlzheimer"sdiseasemousemodelwhenadmiNISTeredatanadvancedstageofdiseaseprogression.
GovindarajanNetal(2011)JAlzheimersDis26(1):187-97.PubMedID:21593570
品牌介绍
Hello Bio是由一群经验丰富的科学家和化学家们创立的充满活力的生物企业，总部位于英国布里斯托尔，在美国普林斯顿设有分公司，主旨在于提供质优价廉的生命科学研究工具，主要产品线为小分子化合物，如激动剂、拮抗剂、抑制剂等，部分产品价格甚至低至其他供应商的50%。热销产品线：酶抑制剂和激动剂ROCK inhibitor Y-27632, PKA inhibitor KT 5720 , adenylyl cyclase activator Forskolin, and novel GRK2/3 inhibitor Cmpd101等。 离子通道调节剂NMDA antagonist D-AP5, sodium channel blocker tetrodotoxin citrate, TRP antagonist capsazepine, and GABAA antagonist SR 95531 等。信号通路工具各种信号通路抑制剂、激动剂表观遗传学研究工具potent HDAC inhibitor Trichostatin A, DNA methyltransferase inhibitor 5-aza-2'-deoxycytidine,BET bromodomain inhibitor (+)-JQ1 and potent,selective GLP / G9a HMTase inhibitor BIX 01294 等受体配体novel selective GRK2/3 inhibitor, NMDA antagonist D-AP5, Group I mGlu agonist (S)-3,5-DHPG, and GABAA antagonist SR 95531.等干细胞调节剂ROCK inhibitor Y-27632, SB 431542 DAPT.
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