Hello Bio/SL 0101-1/HB0584/1mg
市场价：
¥5031.00
美元价：
3870.00
产品分类：
酸碱缓冲液
联系Q Q：
3392242852
电话号码：
4000-520-616
电子邮箱：
info@ebiomall.com
商品介绍
Productoverview
- NameSL0101-1
- ShortdescriptionSelectivep90ribosomalS6kinaseinhibitor
- BIOLOGicaldescriptionSelectivep90ribosomalS6kinase(RSK)inhibitor(IC50=89nMforRSK2).Showsanti-proliferativeactionsagainstcancercelllines.
- AlternativenamesSL0101
- BiologicalactionInhibitor
- Purity>95%
- OurproductsinactionSubmitYourCitationNow
Properties
- Chemicalname3-[(3,4-Di-O-acetyl-6-deoxy-α-L-mannopyranosyl)oxy]-5,7-dihydro-2-(4-hydroxyphenyl)-4H-1benzopyran-4-one
- MolecularWeight516.46
- Chemicalstructure
![SL 0101-1 [77307-50-7]](images/hellobio/201710/hb0584.png "SL 0101-1 [77307-50-7]")
- MolecularFormulaC25H24O12
- CASNumber77307-50-7
StoringandUsingYourProduct
- Storageinstructions-20°C
- Solubilityoverviewsolubleinethanol(20mM)orDMSO(10mM)
- ImportantThisproductisforRESEARCHUSEONLYandisnotintendedfortherapeuticordiagnosticuse.Notforhumanorveterinaryuse.
ReferencesforSL0101-1
Identificationofthefirstspecificinhibitorofp90ribosomalS6kinase(RSK)revealsanunexpectedroleforRSKincancercellproliferation.
SmithJAetal(2005)CancerRes65(3):1027-34.PubMedID:15705904InhibitionofRSK/YB-1signalingenhancestheanti-cancereffectofenzalutamideinprostatecancer.
ShiotaMetal(2014)Prostate74(9):959-69.PubMedID:24740858Theselectivityofproteinkinaseinhibitors:afurtherupdate.
BainJetal(2007)BiochemJ408(3):297-315.PubMedID:17850214
品牌介绍
Hello Bio是由一群经验丰富的科学家和化学家们创立的充满活力的生物企业，总部位于英国布里斯托尔，在美国普林斯顿设有分公司，主旨在于提供质优价廉的生命科学研究工具，主要产品线为小分子化合物，如激动剂、拮抗剂、抑制剂等，部分产品价格甚至低至其他供应商的50%。热销产品线：酶抑制剂和激动剂ROCK inhibitor Y-27632, PKA inhibitor KT 5720 , adenylyl cyclase activator Forskolin, and novel GRK2/3 inhibitor Cmpd101等。 离子通道调节剂NMDA antagonist D-AP5, sodium channel blocker tetrodotoxin citrate, TRP antagonist capsazepine, and GABAA antagonist SR 95531 等。信号通路工具各种信号通路抑制剂、激动剂表观遗传学研究工具potent HDAC inhibitor Trichostatin A, DNA methyltransferase inhibitor 5-aza-2'-deoxycytidine,BET bromodomain inhibitor (+)-JQ1 and potent,selective GLP / G9a HMTase inhibitor BIX 01294 等受体配体novel selective GRK2/3 inhibitor, NMDA antagonist D-AP5, Group I mGlu agonist (S)-3,5-DHPG, and GABAA antagonist SR 95531.等干细胞调节剂ROCK inhibitor Y-27632, SB 431542 DAPT.
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