Hello Bio/Sephin1/HB4296/10mg
市场价：
¥2008.50
美元价：
1545.00
产品分类：
酸碱缓冲液
联系Q Q：
3392242852
电话号码：
4000-520-616
电子邮箱：
info@ebiomall.com
商品介绍
Productoverview
- NameSephin1
- ShortdescriptionSelectivePP1R15Ainhibitor
- BIOLOGicaldescriptionSelectiveinhibitorofthestress-inducedProteinPhosphatase1RegulatorySubunit15A(PP1R15A).Guanabenzderivative.DoesnotbindtherelatedPP1R15B.Protectscellsfromproteinmisfoldingstressandpreventsprotein-misfoldingdiseasessuchasCharcot-Marie-Tooth1Bandamyotrophiclateralsclerosisinvivo.
- AlternativenamesNSC65390
- BiologicalactionInhibitor
- Purity>95%
- OurproductsinactionSubmitYourCitationNow
Properties
- Chemicalname(E)-2-(2-Chlorobenzylidene)hydrazinecarboximidamide
- MolecularWeight196.64
- Chemicalstructure
![Sephin 1 [951441-04-6]](images/hellobio/201710/hb4296.png "Sephin 1 [951441-04-6]")
- MolecularFormulaC8H9ClN4
- CASNumber951441-04-6
- PubChemidentifier9561611
- SMILESC1=CC=C(C(=C1)/C=N/N=C(N)N)Cl
- InChiInChI=1S/C8H9ClN4/c9-7-4-2-1-3-6(7)5-12-13-8(10)11/h1-5H,(H4,10,11,13)/b12-5+
- InChiKeyPDWJALXSRRSUHR-LFYBBSHMSA-N
- MDLnumberMFCD00790608
StoringandUsingYourProduct
- Storageinstructions+4°C
- SolubilityoverviewSolubleinDMSO(100mM)
- ImportantThisproductisforRESEARCHUSEONLYandisnotintendedfortherapeuticordiagnosticuse.Notforhumanorveterinaryuse.
ReferencesforSephin1
Preventingproteostasisdiseasesbyselectiveinhibitionofaphosphataseregulatorysubunit.
DasIetal(2015)Science348(6231):239-42PubMedID:25859045
品牌介绍
Hello Bio是由一群经验丰富的科学家和化学家们创立的充满活力的生物企业，总部位于英国布里斯托尔，在美国普林斯顿设有分公司，主旨在于提供质优价廉的生命科学研究工具，主要产品线为小分子化合物，如激动剂、拮抗剂、抑制剂等，部分产品价格甚至低至其他供应商的50%。热销产品线：酶抑制剂和激动剂ROCK inhibitor Y-27632, PKA inhibitor KT 5720 , adenylyl cyclase activator Forskolin, and novel GRK2/3 inhibitor Cmpd101等。 离子通道调节剂NMDA antagonist D-AP5, sodium channel blocker tetrodotoxin citrate, TRP antagonist capsazepine, and GABAA antagonist SR 95531 等。信号通路工具各种信号通路抑制剂、激动剂表观遗传学研究工具potent HDAC inhibitor Trichostatin A, DNA methyltransferase inhibitor 5-aza-2'-deoxycytidine,BET bromodomain inhibitor (+)-JQ1 and potent,selective GLP / G9a HMTase inhibitor BIX 01294 等受体配体novel selective GRK2/3 inhibitor, NMDA antagonist D-AP5, Group I mGlu agonist (S)-3,5-DHPG, and GABAA antagonist SR 95531.等干细胞调节剂ROCK inhibitor Y-27632, SB 431542 DAPT.
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