Hello Bio/SDZ 220-581/HB0580/
市场价：
¥721.50
美元价：
555.00
产品分类：
酸碱缓冲液
联系Q Q：
3392242852
电话号码：
4000-520-616
电子邮箱：
info@ebiomall.com
商品介绍
Productoverview
- NameSDZ220-581
- ShortdescriptionCompetitiveNMDAreceptorantagoNIST
- BIOLOGicaldescriptionCompetitiveNMDAreceptorantagonist(pKi=7.7).Bloodbrainbarrierpermeable.Decreasesprepulseinhibitionandincreasemotoractivity.Displaysanalgesicproperties.
- BiologicalactionAntagonist
- Purity>98%
- OurproductsinactionSubmitYourCitationNow
Properties
- Chemicalname(S)-α-Amino-2"-chloro-5-(phosphonomethyl)[1,1"-biphenyl]-3-propanoicacid
- MolecularWeight369.74
- Chemicalstructure
![SDZ 220-581 [174575-17-8]](images/hellobio/201710/hb0580.png "SDZ 220-581 [174575-17-8]")
- MolecularFormulaC16H17ClNO5P
- CASNumber174575-17-8
StoringandUsingYourProduct
- Storageinstructionsroomtemperature
- SolubilityoverviewsolubleinDMSO(25mM,gentlewarming)orNaOH(100mM,1.1eqNaOH)
- ImportantThisproductisforRESEARCHUSEONLYandisnotintendedfortherapeuticordiagnosticuse.Notforhumanorveterinaryuse.
ReferencesforSDZ220-581
Biphenyl-derivativesof2-amino-7-phosphono-heptanoicacid,anovelclassofpotentcompetitiveNMDAreceptorantagonists--II.Pharmacologicalcharacterizationinvivo.
UrwylerSetal(1996)Neuropharmacology35(6):655-69.PubMedID:8887975DisruptionofprepulseinhibitionandincreasesinlocomotoractivitybycompetitiveN-methyl-D-aspartatereceptorantagonistsinrats.
BakshiVPetal(1999)JPharmacolExpTher288(2):643-52.PubMedID:9918570Biphenyl-derivativesof2-amino-7-phosphonoheptanoicacid,anovelclassofpotentcompetitiveNMDAreceptorantagonist--I.Pharmacologicalcharacterizationinvitro.
UrwylerSetal(1996)Neuropharmacology35(6):643-54.PubMedID:8887974
品牌介绍
Hello Bio是由一群经验丰富的科学家和化学家们创立的充满活力的生物企业，总部位于英国布里斯托尔，在美国普林斯顿设有分公司，主旨在于提供质优价廉的生命科学研究工具，主要产品线为小分子化合物，如激动剂、拮抗剂、抑制剂等，部分产品价格甚至低至其他供应商的50%。热销产品线：酶抑制剂和激动剂ROCK inhibitor Y-27632, PKA inhibitor KT 5720 , adenylyl cyclase activator Forskolin, and novel GRK2/3 inhibitor Cmpd101等。 离子通道调节剂NMDA antagonist D-AP5, sodium channel blocker tetrodotoxin citrate, TRP antagonist capsazepine, and GABAA antagonist SR 95531 等。信号通路工具各种信号通路抑制剂、激动剂表观遗传学研究工具potent HDAC inhibitor Trichostatin A, DNA methyltransferase inhibitor 5-aza-2'-deoxycytidine,BET bromodomain inhibitor (+)-JQ1 and potent,selective GLP / G9a HMTase inhibitor BIX 01294 等受体配体novel selective GRK2/3 inhibitor, NMDA antagonist D-AP5, Group I mGlu agonist (S)-3,5-DHPG, and GABAA antagonist SR 95531.等干细胞调节剂ROCK inhibitor Y-27632, SB 431542 DAPT.
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