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当前位置: 首页 > 产品中心 > acid_base_buffer_solution > 你好Bio/SCH 23390盐酸盐/HB1643/50mg
商品详细你好Bio/SCH 23390盐酸盐/HB1643/50mg
你好Bio/SCH 23390盐酸盐/HB1643/50mg
你好Bio/SCH 23390盐酸盐/HB1643/50mg
商品编号: HB1643
品牌: hellobio
市场价: ¥7936.50
美元价: 6105.00
产地: 美国(厂家直采)
公司:
产品分类: 酸碱缓冲液
公司分类: acid_base_buffer_solution
联系Q Q: 3392242852
电话号码: 4000-520-616
电子邮箱: info@ebiomall.com
商品介绍

Productoverview

  • Name
    SCH23390hydrochloride
  • Shortdescription
    Potent,selectiveD1-likereceptorantagoNIST
  • BIOLOGicaldescription
    PotentandselectiveD1-likereceptorantagonist(Kivaluesare0.2,0.3,~800,~1100,~3000nMatD1,D5,D3,D2andD4respectively).Alsoactsasanagonistat5-HT1Cand5-HT2C(Kivaluesare6.3and9.3respectively).Showsanxiolyticandanticonvulsanteffects.Activeinvivo.
  • Biologicalaction
    Antagonist
  • Purity
    >98%
  • Ourproductsinaction
    SubmitYourCitationNow

Properties

  • Chemicalname
    (R)-(+)-7-Chloro-8-hydroxy-3-methyl-1-phenyl-2,3,4,5-tetrahydro-1H-3-benzazepinehydrochloride
  • MolecularWeight
    324.24
  • Chemicalstructure
    SCH 23390 hydrochloride [125941-87-9]
  • MolecularFormula
    C17H18ClNO.HCl
  • CASNumber
    125941-87-9

StoringandUsingYourProduct

  • Storageinstructions
    +4°C(desiccate)
  • Important
    ThisproductisforRESEARCHUSEONLYandisnotintendedfortherapeuticordiagnosticuse.Notforhumanorveterinaryuse.

ReferencesforSCH23390hydrochloride

  • The"selective"dopamineD1receptorantagonist,SCH23390,isapotentandhighefficacyagonistatclonedhumanSEROtonin2Creceptors.

    MillanMJetal(2001)Psychopharmacology(Berl)156(1):58-62.
    PubMedID:11465634
  • SCH23390:thefirstselectivedopamineD1-likereceptorantagonist.

    BourneJA(2001)CNSDrugRev7(4):399-414.
    PubMedID:11830757
  • SelectiveblockadeofdopamineD-1receptorbySCH23390affectsdopamineagonistbindingto3H-spiperonelabeledD-2receptorsinratstriatum.

    ZhangXetal(1989)JpnJPharmacol50(3):333-45.
    PubMedID:2569545
品牌介绍
Hello Bio是由一群经验丰富的科学家和化学家们创立的充满活力的生物企业,总部位于英国布里斯托尔,在美国普林斯顿设有分公司,主旨在于提供质优价廉的生命科学研究工具,主要产品线为小分子化合物,如激动剂、拮抗剂、抑制剂等,部分产品价格甚至低至其他供应商的50%。热销产品线:酶抑制剂和激动剂ROCK inhibitor Y-27632, PKA inhibitor KT 5720 , adenylyl cyclase activator Forskolin, and novel GRK2/3 inhibitor Cmpd101等。 离子通道调节剂NMDA antagonist D-AP5, sodium channel blocker tetrodotoxin citrate, TRP antagonist capsazepine, and GABAA antagonist SR 95531 等。信号通路工具各种信号通路抑制剂、激动剂表观遗传学研究工具potent HDAC inhibitor Trichostatin A, DNA methyltransferase inhibitor 5-aza-2'-deoxycytidine,BET bromodomain inhibitor (+)-JQ1 and potent,selective GLP / G9a HMTase inhibitor BIX 01294 等受体配体novel selective GRK2/3 inhibitor,  NMDA antagonist D-AP5, Group I mGlu agonist (S)-3,5-DHPG, and GABAA antagonist SR 95531.等干细胞调节剂ROCK inhibitor Y-27632,  SB 431542 DAPT.