你好Bio/SCH 23390盐酸盐/HB1643/50mg
市场价:
¥7936.50
美元价:
6105.00
产品分类:
酸碱缓冲液
联系Q Q:
3392242852
电话号码:
4000-520-616
电子邮箱:
info@ebiomall.com
商品介绍
Productoverview
- NameSCH23390hydrochloride
- ShortdescriptionPotent,selectiveD1-likereceptorantagoNIST
- BIOLOGicaldescriptionPotentandselectiveD1-likereceptorantagonist(Kivaluesare0.2,0.3,~800,~1100,~3000nMatD1,D5,D3,D2andD4respectively).Alsoactsasanagonistat5-HT1Cand5-HT2C(Kivaluesare6.3and9.3respectively).Showsanxiolyticandanticonvulsanteffects.Activeinvivo.
- BiologicalactionAntagonist
- Purity>98%
- OurproductsinactionSubmitYourCitationNow
Properties
- Chemicalname(R)-(+)-7-Chloro-8-hydroxy-3-methyl-1-phenyl-2,3,4,5-tetrahydro-1H-3-benzazepinehydrochloride
- MolecularWeight324.24
- Chemicalstructure
- MolecularFormulaC17H18ClNO.HCl
- CASNumber125941-87-9
StoringandUsingYourProduct
- Storageinstructions+4°C(desiccate)
- ImportantThisproductisforRESEARCHUSEONLYandisnotintendedfortherapeuticordiagnosticuse.Notforhumanorveterinaryuse.
ReferencesforSCH23390hydrochloride
The"selective"dopamineD1receptorantagonist,SCH23390,isapotentandhighefficacyagonistatclonedhumanSEROtonin2Creceptors.
MillanMJetal(2001)Psychopharmacology(Berl)156(1):58-62.PubMedID:11465634SCH23390:thefirstselectivedopamineD1-likereceptorantagonist.
BourneJA(2001)CNSDrugRev7(4):399-414.PubMedID:11830757SelectiveblockadeofdopamineD-1receptorbySCH23390affectsdopamineagonistbindingto3H-spiperonelabeledD-2receptorsinratstriatum.
ZhangXetal(1989)JpnJPharmacol50(3):333-45.PubMedID:2569545
品牌介绍
Hello Bio是由一群经验丰富的科学家和化学家们创立的充满活力的生物企业,总部位于英国布里斯托尔,在美国普林斯顿设有分公司,主旨在于提供质优价廉的生命科学研究工具,主要产品线为小分子化合物,如激动剂、拮抗剂、抑制剂等,部分产品价格甚至低至其他供应商的50%。热销产品线:酶抑制剂和激动剂ROCK inhibitor Y-27632, PKA inhibitor KT 5720 , adenylyl cyclase activator Forskolin, and novel GRK2/3 inhibitor Cmpd101等。 离子通道调节剂NMDA antagonist D-AP5, sodium channel blocker tetrodotoxin citrate, TRP antagonist capsazepine, and GABAA antagonist SR 95531 等。信号通路工具各种信号通路抑制剂、激动剂表观遗传学研究工具potent HDAC inhibitor Trichostatin A, DNA methyltransferase inhibitor 5-aza-2'-deoxycytidine,BET bromodomain inhibitor (+)-JQ1 and potent,selective GLP / G9a HMTase inhibitor BIX 01294 等受体配体novel selective GRK2/3 inhibitor, NMDA antagonist D-AP5, Group I mGlu agonist (S)-3,5-DHPG, and GABAA antagonist SR 95531.等干细胞调节剂ROCK inhibitor Y-27632, SB 431542 DAPT.
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