Hello Bio/Saclofen/HB0963/
市场价：
¥1345.50
美元价：
1035.00
产品分类：
酸碱缓冲液
联系Q Q：
3392242852
电话号码：
4000-520-616
电子邮箱：
info@ebiomall.com
商品介绍
Productoverview
Properties
- Chemicalname(RS)-3-Amino-2-(4-chlorophenyl)propylsulfonicacid
- MolecularWeight249.72
- Chemicalstructure
![Saclofen [125464-42-8]](images/hellobio/201710/hb0963.png "Saclofen [125464-42-8]")
- MolecularFormulaC9H12ClNO3S
- CASNumber125464-42-8
- PubChemidentifier122150
- SMILESC1=CC(=CC=C1C(CN)CS(=O)(=O)O)Cl
- InChiInChI=1S/C9H12ClNO3S/c10-9-3-1-7(2-4-9)8(5-11)6-15(12,13)14/h1-4,8H,5-6,11H2,(H,12,13,14)
- InChiKeyJYLNVJYYQQXNEK-UHFFFAOYSA-N
- MDLnumberMFCD00216817
StoringandUsingYourProduct
- StorageinstructionsRoomtemperature
- SolubilityoverviewSolubleinwater(10mM)
- ImportantThisproductisforRESEARCHUSEONLYandisnotintendedfortherapeuticordiagnosticuse.Notforhumanorveterinaryuse.
ReferencesforSaclofen
ProposedantagonistsatGABABreceptorsthatinhibitadenylylcyclaseincerebellargranulecellculturesofrat.
HolopainenIetal(1992)EurJPharmacol227(2):225-8.PubMedID:1330652Inhibitionofbaclofenbindingtoratcerebellarmembranesbyphaclofen,saclofen,3-aminopropylphosphonicacidandrelatedGABABreceptorantagonists.
DrewCAetal(1990)NeurosciLett113(1):107-10.PubMedID:2164173AntagonismatGABABreceptorsbysaclofenandrelatedsulphonicanaloguesofbaclofenandGABA.
KerrDIetal(1989)NeurosciLett107(1-3):239-44.PubMedID:2559370
品牌介绍
Hello Bio是由一群经验丰富的科学家和化学家们创立的充满活力的生物企业，总部位于英国布里斯托尔，在美国普林斯顿设有分公司，主旨在于提供质优价廉的生命科学研究工具，主要产品线为小分子化合物，如激动剂、拮抗剂、抑制剂等，部分产品价格甚至低至其他供应商的50%。热销产品线：酶抑制剂和激动剂ROCK inhibitor Y-27632, PKA inhibitor KT 5720 , adenylyl cyclase activator Forskolin, and novel GRK2/3 inhibitor Cmpd101等。 离子通道调节剂NMDA antagonist D-AP5, sodium channel blocker tetrodotoxin citrate, TRP antagonist capsazepine, and GABAA antagonist SR 95531 等。信号通路工具各种信号通路抑制剂、激动剂表观遗传学研究工具potent HDAC inhibitor Trichostatin A, DNA methyltransferase inhibitor 5-aza-2'-deoxycytidine,BET bromodomain inhibitor (+)-JQ1 and potent,selective GLP / G9a HMTase inhibitor BIX 01294 等受体配体novel selective GRK2/3 inhibitor, NMDA antagonist D-AP5, Group I mGlu agonist (S)-3,5-DHPG, and GABAA antagonist SR 95531.等干细胞调节剂ROCK inhibitor Y-27632, SB 431542 DAPT.
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