Hello Bio/Rufinamide/HB1039/100mg
市场价：
¥12675.00
美元价：
9750.00
产品分类：
酸碱缓冲液
联系Q Q：
3392242852
电话号码：
4000-520-616
电子邮箱：
info@ebiomall.com
商品介绍
Product overview
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NameRufinamide
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Short descriptionNa+ channel blocker
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Biological descriptionNa+ channel blocker. Shows higher selectivity for Nav1.7. Also mGluR5 antagonist. A novel triazole derivative. Prolongs sodium channel inactivation. Displays anticonvulsant and antiepileptic actions.
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Biological actionBlocker
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Purity>99%
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Our products in actionSubmit Your Citation Now
Properties
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Chemical name1-[(2,6-Difluorophenyl)methyl]-1H-1,2,3-triazole-4-carboxamide
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Molecular Weight238.19
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Chemical structure
![Rufinamide [106308-44-5]](images/hellobio/201710/hb1039.png "Rufinamide [106308-44-5]")
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Molecular FormulaC10H8F2N4O
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CAS Number106308-44-5
Storing and Using Your Product
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Storage instructionsroom temperature (desiccate)
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Solubility overviewsoluble in DMSO (100mM)
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ImportantThis product is for RESEARCH USE ONLY and is not intended for therapeutic or diagnostic use. Not for human or veterinary use.
References for Rufinamide
Rufinamide.
Arroyo S (2007) Neurotherapeutics 4(1) : 155-62.PubMedID: 17199032Rufinamide attenuates mechanical allodynia in a model of neuropathic pain in the mouse and stabilizes voltage-gated sodium channel inactivated state.
Suter MR et al (2013) Anesthesiology 118(1) : 160-72.PubMedID: 23221868Rufinamide.
Deeks ED et al (2006) CNS Drugs 20(9) : 751-60PubMedID: 16953653
品牌介绍
Hello Bio是由一群经验丰富的科学家和化学家们创立的充满活力的生物企业，总部位于英国布里斯托尔，在美国普林斯顿设有分公司，主旨在于提供质优价廉的生命科学研究工具，主要产品线为小分子化合物，如激动剂、拮抗剂、抑制剂等，部分产品价格甚至低至其他供应商的50%。热销产品线：酶抑制剂和激动剂ROCK inhibitor Y-27632, PKA inhibitor KT 5720 , adenylyl cyclase activator Forskolin, and novel GRK2/3 inhibitor Cmpd101等。 离子通道调节剂NMDA antagonist D-AP5, sodium channel blocker tetrodotoxin citrate, TRP antagonist capsazepine, and GABAA antagonist SR 95531 等。信号通路工具各种信号通路抑制剂、激动剂表观遗传学研究工具potent HDAC inhibitor Trichostatin A, DNA methyltransferase inhibitor 5-aza-2'-deoxycytidine,BET bromodomain inhibitor (+)-JQ1 and potent,selective GLP / G9a HMTase inhibitor BIX 01294 等受体配体novel selective GRK2/3 inhibitor, NMDA antagonist D-AP5, Group I mGlu agonist (S)-3,5-DHPG, and GABAA antagonist SR 95531.等干细胞调节剂ROCK inhibitor Y-27632, SB 431542 DAPT.
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