你好Bio/Ro 61-8048/HB0556/
市场价：
¥721.50
美元价：
555.00
产品分类：
酸碱缓冲液
联系Q Q：
3392242852
电话号码：
4000-520-616
电子邮箱：
info@ebiomall.com
商品介绍
Productoverview
- NameRo61-8048
- ShortdescriptionPotent,competitivekynurenine3-hydroxylaseinhibitor
- BIOLOGicaldescription
- BiologicalactionInhibitor
- Purity>99%
- OurproductsinactionSubmitYourCitationNow
Properties
- Chemicalname3,4-Dimethoxy-N-[4-(3-nitrophenyl)-2-thiazolyl]benzenesulfonamide
- MolecularWeight421.45
- Chemicalstructure
![Ro 61-8048 [199666-03-0]](images/hellobio/201710/hb0556.png "Ro 61-8048 [199666-03-0]")
- MolecularFormulaC17H15N3O6S2
- CASNumber199666-03-0
StoringandUsingYourProduct
- Storageinstructions+4°C
- SolubilityoverviewsolubleinDMSO(100mM)orethanol(10mM)
- ImportantThisproductisforRESEARCHUSEONLYandisnotintendedfortherapeuticordiagnosticuse.Notforhumanorveterinaryuse.
ReferencesforRo61-8048
SynthesisandbiochemicalevaluationofN-(4-phenylthiazol-2-yl)benzenesulfonamidesashigh-affinityinhibitorsofkynurenine3-hydroxylase.
RöverSetal(1997)JMedChem40(26):4378-85.PubMedID:9435907Thekynurenine3-hydroxylaseinhibitorRo61-8048improvesdystoniainageneticmodelofparoxysmaldyskinesia.
RichterAetal(2003)EurJPharmacol478(1):47-52.PubMedID:14555184Kynureninesinthemammalianbrain:whenphysiologymeetspathology.
SchwarczRetal(2012)NatRevNeurosci13(7):465-77.PubMedID:22678511
品牌介绍
Hello Bio是由一群经验丰富的科学家和化学家们创立的充满活力的生物企业，总部位于英国布里斯托尔，在美国普林斯顿设有分公司，主旨在于提供质优价廉的生命科学研究工具，主要产品线为小分子化合物，如激动剂、拮抗剂、抑制剂等，部分产品价格甚至低至其他供应商的50%。热销产品线：酶抑制剂和激动剂ROCK inhibitor Y-27632, PKA inhibitor KT 5720 , adenylyl cyclase activator Forskolin, and novel GRK2/3 inhibitor Cmpd101等。 离子通道调节剂NMDA antagonist D-AP5, sodium channel blocker tetrodotoxin citrate, TRP antagonist capsazepine, and GABAA antagonist SR 95531 等。信号通路工具各种信号通路抑制剂、激动剂表观遗传学研究工具potent HDAC inhibitor Trichostatin A, DNA methyltransferase inhibitor 5-aza-2'-deoxycytidine,BET bromodomain inhibitor (+)-JQ1 and potent,selective GLP / G9a HMTase inhibitor BIX 01294 等受体配体novel selective GRK2/3 inhibitor, NMDA antagonist D-AP5, Group I mGlu agonist (S)-3,5-DHPG, and GABAA antagonist SR 95531.等干细胞调节剂ROCK inhibitor Y-27632, SB 431542 DAPT.
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