Hello Bio/QX 314 bromide/HB1029/100mM (add 1ml water)
市场价：
¥585.00
美元价：
450.00
产品分类：
酸碱缓冲液
联系Q Q：
3392242852
电话号码：
4000-520-616
电子邮箱：
info@ebiomall.com
商品介绍
Product overview
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NameQX 314 bromide
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Short descriptionMembrane impermeable Na+ channel blocker
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Biological description
Membrane impermeable Na+ channel blocker. A quaternary derivative of lidocaine. Reduces amplitude of high threshold Ca2+ currents in CA1 neurons. Displays anesthetic properties. QX 314 chloride also available.
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Alternative namesN-Ethyllidocaine bromide
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Biological actionBlocker
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Purity>98%
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Our products in action1 citation Submit Your Citation Now
Images
Properties
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Chemical nameN-(2,6-Dimethylphenylcarbamoylmethyl)triethylammonium bromide
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Molecular Weight343.31
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Chemical structure
![QX 314 bromide [24003-58-5]](images/hellobio/201710/hb1029.png "QX 314 bromide [24003-58-5]")
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Molecular FormulaC16H27N2OBr
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CAS Number24003-58-5
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PubChem identifier9884487
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SMILESCC[N+](CC)(CC)CC(=O)NC1=C(C=CC=C1C)C.[Br-]
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SourceSynthetic
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InChiInChI=1S/C16H26N2O.BrH/c1-6-18(7-2,8-3)12-15(19)17-16-13(4)10-9-11-14(16)5;/h9-11H,6-8,12H2,1-5H3;1H
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InChiKeyDLHMKHREUTXMCH-UHFFFAOYSA-N
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AppearanceWhite solid
Storing and Using Your Product
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Storage instructionsRoom temperature (desiccate)
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Solubility overviewSoluble in water (100mM)
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ImportantThis product is for RESEARCH USE ONLY and is not intended for therapeutic or diagnostic use. Not for human or veterinary use.
References for QX 314 bromide
Intracellular QX-314 inhibits calcium currents in hippocampal CA1 pyramidal neurons.
Talbot MJ et al (1996) J Neurophysiol 76(3) : 2120-4.PubMedID: 8890325Fast sodium action potentials are generated in the distal apical dendrites of rat hippocampal CA1 pyramidal cells.
Colling SB et al (1994) Neurosci Lett 172(1-2) : 73-96.PubMedID: 8084540The inhibition of sodium currents in myelinated nerve by quaternary derivatives of lidocaine.
Strichartz GR (1973) J Gen Physiol 62(1) : 37-57.PubMedID: 4541340
品牌介绍
Hello Bio是由一群经验丰富的科学家和化学家们创立的充满活力的生物企业，总部位于英国布里斯托尔，在美国普林斯顿设有分公司，主旨在于提供质优价廉的生命科学研究工具，主要产品线为小分子化合物，如激动剂、拮抗剂、抑制剂等，部分产品价格甚至低至其他供应商的50%。热销产品线：酶抑制剂和激动剂ROCK inhibitor Y-27632, PKA inhibitor KT 5720 , adenylyl cyclase activator Forskolin, and novel GRK2/3 inhibitor Cmpd101等。 离子通道调节剂NMDA antagonist D-AP5, sodium channel blocker tetrodotoxin citrate, TRP antagonist capsazepine, and GABAA antagonist SR 95531 等。信号通路工具各种信号通路抑制剂、激动剂表观遗传学研究工具potent HDAC inhibitor Trichostatin A, DNA methyltransferase inhibitor 5-aza-2'-deoxycytidine,BET bromodomain inhibitor (+)-JQ1 and potent,selective GLP / G9a HMTase inhibitor BIX 01294 等受体配体novel selective GRK2/3 inhibitor, NMDA antagonist D-AP5, Group I mGlu agonist (S)-3,5-DHPG, and GABAA antagonist SR 95531.等干细胞调节剂ROCK inhibitor Y-27632, SB 431542 DAPT.
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