Hello Bio/Psalmotoxin 1/HB1148/100μg
市场价：
¥3159.00
美元价：
2430.00
产品分类：
酸碱缓冲液
联系Q Q：
3392242852
电话号码：
4000-520-616
电子邮箱：
info@ebiomall.com
商品介绍
Product overview
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NamePsalmotoxin 1
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Short descriptionPotent, selective ASIC1a blocker
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Biological descriptionPotent and selective acid sensing (proton gated) ion channel 1a (ASIC1a) blocker (IC50 = 0.9 nM). Shows antinociceptive and neuroprotective actions.
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Biological actionBlocker
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Our products in action1 citation Submit Your Citation Now
Images
Properties
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Molecular Weight4689.41
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Molecular FormulaC200H312N62O57S6
Storing and Using Your Product
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Storage instructions-20°C
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Solubility overviewsoluble in water (2mg/ml)
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ImportantThis product is for RESEARCH USE ONLY and is not intended for therapeutic or diagnostic use. Not for human or veterinary use.
References for Psalmotoxin 1
Isolation of a tarantula toxin specific for a class of proton-gated Na+ channels.
Escoubas P et al (2000) J Biol Chem 275(33) : 25116-21.PubMedID: 10829030A tarantula peptide against pain via ASIC1a channels and opioid mechanisms.
Mazzuca M et al (2007) Nat Neurosci 10(8) : 943-5.PubMedID: 17632507Neuroprotective effect of acid-sensing ion channel inhibitor psalmotoxin-1 after hypoxia-ischemia in newborn piglet striatum.
Yang ZJ et al (2011) Neurobiol Dis 43(2) : 446-54.PubMedID: 21558004
品牌介绍
Hello Bio是由一群经验丰富的科学家和化学家们创立的充满活力的生物企业，总部位于英国布里斯托尔，在美国普林斯顿设有分公司，主旨在于提供质优价廉的生命科学研究工具，主要产品线为小分子化合物，如激动剂、拮抗剂、抑制剂等，部分产品价格甚至低至其他供应商的50%。热销产品线：酶抑制剂和激动剂ROCK inhibitor Y-27632, PKA inhibitor KT 5720 , adenylyl cyclase activator Forskolin, and novel GRK2/3 inhibitor Cmpd101等。 离子通道调节剂NMDA antagonist D-AP5, sodium channel blocker tetrodotoxin citrate, TRP antagonist capsazepine, and GABAA antagonist SR 95531 等。信号通路工具各种信号通路抑制剂、激动剂表观遗传学研究工具potent HDAC inhibitor Trichostatin A, DNA methyltransferase inhibitor 5-aza-2'-deoxycytidine,BET bromodomain inhibitor (+)-JQ1 and potent,selective GLP / G9a HMTase inhibitor BIX 01294 等受体配体novel selective GRK2/3 inhibitor, NMDA antagonist D-AP5, Group I mGlu agonist (S)-3,5-DHPG, and GABAA antagonist SR 95531.等干细胞调节剂ROCK inhibitor Y-27632, SB 431542 DAPT.
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