Hello Bio/PP 3/HB1336/10mg
市场价：
¥2827.50
美元价：
2175.00
产品分类：
酸碱缓冲液
联系Q Q：
3392242852
电话号码：
4000-520-616
电子邮箱：
info@ebiomall.com
商品介绍
Productoverview
- NamePP3
- ShortdescriptionPP2negativecontrol
- BIOLOGicaldescriptionPP2(Srckinaseinhibitor)negativecontrol.DoesnotinhibitSrcfamilykinases.InhibitsEGFRkinaseandCK1δ(IC50valuesare2.7and9.9µMrespectively).
- BiologicalactionInhibitor
- Purity>98%
- OurproductsinactionSubmitYourCitationNow
Properties
- Chemicalname1-Phenyl-1H-pyrazolo[3,4-d]pyrimidin-4-amine
- MolecularWeight211.22
- MolecularFormulaC11H9N5
- CASNumber5334-30-5
StoringandUsingYourProduct
- Storageinstructions-20°C
- SolubilityoverviewsolubleinDMSO(100mM)orethanol(25mM)
- ImportantThisproductisforRESEARCHUSEONLYandisnotintendedfortherapeuticordiagnosticuse.Notforhumanorveterinaryuse.
ReferencesforPP3
SrcfamilykinaseinhibitorPP2efficientlyinhibitscervicalcancercellproliferationthroughdown-regulatingphospho-Src-Y416andphospho-EGFR-Y1173.
KongLetal(2011)MolCellBiochem348(1-2):11-9.PubMedID:21052789Thespecificitiesofproteinkinaseinhibitors:anupdate.
BainJetal(2003)BiochemJ371(Pt1):199-204.PubMedID:12534346UseofapharmacophoremodelforthedesignofEGF-Rtyrosinekinaseinhibitors:4-(phenylamino)pyrazolo[3,4-d]pyrimidines.
TraxlerPetal(1997)JMedChem40(22):3601-16.PubMedID:9357527
品牌介绍
Hello Bio是由一群经验丰富的科学家和化学家们创立的充满活力的生物企业，总部位于英国布里斯托尔，在美国普林斯顿设有分公司，主旨在于提供质优价廉的生命科学研究工具，主要产品线为小分子化合物，如激动剂、拮抗剂、抑制剂等，部分产品价格甚至低至其他供应商的50%。热销产品线：酶抑制剂和激动剂ROCK inhibitor Y-27632, PKA inhibitor KT 5720 , adenylyl cyclase activator Forskolin, and novel GRK2/3 inhibitor Cmpd101等。 离子通道调节剂NMDA antagonist D-AP5, sodium channel blocker tetrodotoxin citrate, TRP antagonist capsazepine, and GABAA antagonist SR 95531 等。信号通路工具各种信号通路抑制剂、激动剂表观遗传学研究工具potent HDAC inhibitor Trichostatin A, DNA methyltransferase inhibitor 5-aza-2'-deoxycytidine,BET bromodomain inhibitor (+)-JQ1 and potent,selective GLP / G9a HMTase inhibitor BIX 01294 等受体配体novel selective GRK2/3 inhibitor, NMDA antagonist D-AP5, Group I mGlu agonist (S)-3,5-DHPG, and GABAA antagonist SR 95531.等干细胞调节剂ROCK inhibitor Y-27632, SB 431542 DAPT.
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