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Hello Bio/PKA inhibitor fragment (6-22) amide/HB0508/500μg
Hello Bio/PKA inhibitor fragment (6-22) amide/HB0508/500μg
市场价：
¥1423.50
美元价：
1095.00
产品分类：
酸碱缓冲液
联系Q Q：
3392242852
电话号码：
4000-520-616
电子邮箱：
info@ebiomall.com
商品介绍
Productoverview
- NamePKAinhibitorfragment(6-22)amide
- ShortdescriptionPotentPKAinhibitor
- BIOLOGicaldescriptionPotentproteinkinaseA(PKA)inhibitor(Ki=1.6nM).Decreaseslong-termpotentiation(LTP)athippocampalsynapses.Reversesmorphinetolerance.
- BiologicalactionInhibitor
- OurproductsinactionSubmitYourCitationNow
Properties
- MolecularWeight1868.08
- MolecularFormulaC80H130N28O24
- CASNumber121932-06-7
StoringandUsingYourProduct
- Storageinstructions-20°C(desiccate)
- Solubilityoverviewsolubleinacetonitrile
- ImportantThisproductisforRESEARCHUSEONLYandisnotintendedfortherapeuticordiagnosticuse.Notforhumanorveterinaryuse.
ReferencesforPKAinhibitorfragment(6-22)amide
Proteinkinaseinhibitor-(6-22)-amidepeptideanalogswithstandardandnonstandardaminoacidsubstitutionsforphenylalanine10.InhibitionofcAMP-dependentproteinkinase.
GlassDBetal(1989)JBiolChem264(24):14579-84.PubMedID:2760075InhibitionofthecAMPpathwaydecreasesearlylong-termpotentiationatCA1hippocampalsynapses.
OtmakhovaNAetal(2000)JNeurosci20(12):4446-51.PubMedID:10844013AlterationsinbrainProteinKinaseAactivityandreversalofmorphinetolerancebytwofragmentsofnativeProteinKinaseAinhibitorpeptide(PKI).
DaltonGDetal(2005)Neuropharmacology48(5):648-57.PubMedID:15814100
品牌介绍
Hello Bio是由一群经验丰富的科学家和化学家们创立的充满活力的生物企业，总部位于英国布里斯托尔，在美国普林斯顿设有分公司，主旨在于提供质优价廉的生命科学研究工具，主要产品线为小分子化合物，如激动剂、拮抗剂、抑制剂等，部分产品价格甚至低至其他供应商的50%。热销产品线：酶抑制剂和激动剂ROCK inhibitor Y-27632, PKA inhibitor KT 5720 , adenylyl cyclase activator Forskolin, and novel GRK2/3 inhibitor Cmpd101等。 离子通道调节剂NMDA antagonist D-AP5, sodium channel blocker tetrodotoxin citrate, TRP antagonist capsazepine, and GABAA antagonist SR 95531 等。信号通路工具各种信号通路抑制剂、激动剂表观遗传学研究工具potent HDAC inhibitor Trichostatin A, DNA methyltransferase inhibitor 5-aza-2'-deoxycytidine,BET bromodomain inhibitor (+)-JQ1 and potent,selective GLP / G9a HMTase inhibitor BIX 01294 等受体配体novel selective GRK2/3 inhibitor, NMDA antagonist D-AP5, Group I mGlu agonist (S)-3,5-DHPG, and GABAA antagonist SR 95531.等干细胞调节剂ROCK inhibitor Y-27632, SB 431542 DAPT.
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