Hello Bio/Pifithrin-μ/HB3025/25mg
商品编号：
HB3025-5mg
品牌：
hellobio
市场价：
¥897.00
美元价：
690.00
产品分类：
酸碱缓冲液
联系Q Q：
3392242852
电话号码：
4000-520-616
电子邮箱：
info@ebiomall.com
商品介绍
Product overview
-
NamePifithrin-μ
-
Short descriptionp53 inhibitor. Supresses eSC self renewal.
-
Biological descriptionp53-mitochondrial binding inhibitor which inhibits p53-mediated apoptosis. Also a HSP70 inhibitor. Supresses embroynic stem cell (eSC) self renewal.
-
Biological actionInhibitor
-
Purity>99%
-
Our products in actionSubmit Your Citation Now
Properties
-
Chemical name2-Phenylethynesulfonamide
-
Molecular Weight181.21
-
Chemical structure
![Pifithrin-µ | [64984-31-2]](images/hellobio/201710/hb3025.png "Pifithrin-µ | [64984-31-2]")
-
Molecular FormulaC8H7NO2S
-
CAS Number64984-31-2
Storing and Using Your Product
-
Storage instructions+4°C
-
Solubility overviewsoluble in DMSO (100mM) or ethanol (100mM)
-
ImportantThis product is for RESEARCH USE ONLY and is not intended for therapeutic or diagnostic use. Not for human or veterinary use.
References for Pifithrin-μ
The HSP70 and autophagy inhibitor pifithrin-μ enhances the antitumor effects of TRAIL on human pancreatic cancer.
Monma et al (2013) Mol Cancer Ther 12(4) : 341-51PubMedID: 23371857Linking the p53 tumour suppressor pathway to somatic cell reprogramming.
Kawamura et al (2009) Nature 460(7259) : 1140-4PubMedID: 19668186Prevention of chemotherapy-induced peripheral neuropathy by the small-molecule inhibitor pifithrin-μ.
Krukowski et al (2015) Pain 156(11) : 2184-92PubMedID: 26473292
品牌介绍
Hello Bio是由一群经验丰富的科学家和化学家们创立的充满活力的生物企业，总部位于英国布里斯托尔，在美国普林斯顿设有分公司，主旨在于提供质优价廉的生命科学研究工具，主要产品线为小分子化合物，如激动剂、拮抗剂、抑制剂等，部分产品价格甚至低至其他供应商的50%。热销产品线：酶抑制剂和激动剂ROCK inhibitor Y-27632, PKA inhibitor KT 5720 , adenylyl cyclase activator Forskolin, and novel GRK2/3 inhibitor Cmpd101等。 离子通道调节剂NMDA antagonist D-AP5, sodium channel blocker tetrodotoxin citrate, TRP antagonist capsazepine, and GABAA antagonist SR 95531 等。信号通路工具各种信号通路抑制剂、激动剂表观遗传学研究工具potent HDAC inhibitor Trichostatin A, DNA methyltransferase inhibitor 5-aza-2'-deoxycytidine,BET bromodomain inhibitor (+)-JQ1 and potent,selective GLP / G9a HMTase inhibitor BIX 01294 等受体配体novel selective GRK2/3 inhibitor, NMDA antagonist D-AP5, Group I mGlu agonist (S)-3,5-DHPG, and GABAA antagonist SR 95531.等干细胞调节剂ROCK inhibitor Y-27632, SB 431542 DAPT.
联络我们
