
Hello Bio/Piceatannol/HB0505/10mg
商品编号:
HB0505-10mg
品牌:
hellobio
市场价:
¥2067.00
美元价:
1590.00
产品分类:
酸碱缓冲液
联系Q Q:
3392242852
电话号码:
4000-520-616
电子邮箱:
info@ebiomall.com
商品介绍
Product overview
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NamePiceatannol
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Short descriptionSyk tyrosine kinase / JAK-1 inhibitor
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Biological descriptionSyk tyrosine kinase inhibitor (IC50 = 1.53 µM). Also JAK-1 inhibitor. Analog of resveratrol. Shows many biological actions such as growth-inhibitory, anti-oxidant, anti-inflammatory, cardiovascular and pro-apoptotic effects.
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Biological actionInhibitor
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Purity>98%
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Properties
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Chemical name3,5,3',4'-Tetrahydroxystilbene
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Molecular Weight244.3
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Chemical structure
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Molecular FormulaC14H12O4
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CAS Number10083-24-6
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PubChem identifier667639
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SMILESC1=CC(=C(C=C1C=CC2=CC(=CC(=C2)O)O)O)O
Storing and Using Your Product
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Solubility overviewsoluble in DMSO (10mg/ml) or DMF
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ImportantThis product is for RESEARCH USE ONLY and is not intended for therapeutic or diagnostic use. Not for human or veterinary use.
References for Piceatannol
Biological activity of piceatannol: leaving the shadow of resveratrol.
Piotrowska H et al (2012) Mutat Res 750(1) : 60-82.PubMedID: 22108298Piceatannol, a derivative of resveratrol, moderately slows I(Na) inactivation and exerts antiarrhythmic action in ischaemia-reperfused rat hearts.
Chen WP et al (2009) Br J Pharmacol 157(3) : 381-91.PubMedID: 19371352Piceatannol inhibits melanogenesis by its antioxidative actions.
Yokozawa T et al (2007) Biol Pharm Bull 30(11) : 2007-11.PubMedID: 17978467
品牌介绍
Hello Bio是由一群经验丰富的科学家和化学家们创立的充满活力的生物企业,总部位于英国布里斯托尔,在美国普林斯顿设有分公司,主旨在于提供质优价廉的生命科学研究工具,主要产品线为小分子化合物,如激动剂、拮抗剂、抑制剂等,部分产品价格甚至低至其他供应商的50%。热销产品线:酶抑制剂和激动剂ROCK inhibitor Y-27632, PKA inhibitor KT 5720 , adenylyl cyclase activator Forskolin, and novel GRK2/3 inhibitor Cmpd101等。 离子通道调节剂NMDA antagonist D-AP5, sodium channel blocker tetrodotoxin citrate, TRP antagonist capsazepine, and GABAA antagonist SR 95531 等。信号通路工具各种信号通路抑制剂、激动剂表观遗传学研究工具potent HDAC inhibitor Trichostatin A, DNA methyltransferase inhibitor 5-aza-2'-deoxycytidine,BET bromodomain inhibitor (+)-JQ1 and potent,selective GLP / G9a HMTase inhibitor BIX 01294 等受体配体novel selective GRK2/3 inhibitor, NMDA antagonist D-AP5, Group I mGlu agonist (S)-3,5-DHPG, and GABAA antagonist SR 95531.等干细胞调节剂ROCK inhibitor Y-27632, SB 431542 DAPT.
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