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当前位置: 首页 > 产品中心 > acid_base_buffer_solution > Hello Bio/Phloretin/HB0500/1g
商品详细Hello Bio/Phloretin/HB0500/1g
Hello Bio/Phloretin/HB0500/1g
Hello Bio/Phloretin/HB0500/1g
商品编号: HB0500-1g
品牌: hellobio
市场价: ¥6727.50
美元价: 5175.00
产地: 美国(厂家直采)
公司:
产品分类: 酸碱缓冲液
公司分类: acid_base_buffer_solution
联系Q Q: 3392242852
电话号码: 4000-520-616
电子邮箱: info@ebiomall.com
商品介绍

Productoverview

  • Name
    Phloretin
  • Shortdescription
    PKCinhibitor
  • BIOLOGicaldescription
    ProteinkinaseC(PKC)inhibitor.PGF2areceptorantagoNIST(IC50=16µM).InhibitsGLUT2glucosetransport.Showsapoptotic,antitumor,antioxidantandimmunomodulatoryactions.
  • Biologicalaction
    Inhibitor
  • Purity
    >98%
  • Ourproductsinaction
    SubmitYourCitationNow

Properties

  • MolecularWeight
    274.26
  • Chemicalstructure
    Phloretin [60-82-2]
  • MolecularFormula
    C15H14O5
  • CASNumber
    60-82-2
  • PubChemidentifier
    4788
  • SMILES
    OC1=CC=C(CCC(=O)C2=C(O)C=C(O)C=C2O)C=C1

StoringandUsingYourProduct

  • Solubilityoverview
    solubleinethanolormethanol
  • Important
    ThisproductisforRESEARCHUSEONLYandisnotintendedfortherapeuticordiagnosticuse.Notforhumanorveterinaryuse.

ReferencesforPhloretin

  • Immunomodulationofphloretinbyimpairingdendriticcellactivationandfunction.

    LinCCetal(2014)FoodFunct5(5):997-1006.
    PubMedID:24651121
  • Phloretin-inducedapoptosisinB16melanoma4A5cellsandHL60humanleukemiacells.

    KoboriMetal(1999)BiosciBiotechnolBiochem63(4):719-25.
    PubMedID:10361685
  • PhloretinasanantagonistofprostaglandinF2alphareceptorinculturedratastrocytes.

    KitanakaJetal(1993)JNeuRochem60(2):704-8.
    PubMedID:8093482
  • Invitroandinvivostudyofphloretin-inducedapoptosisinhumanlivercancercellsinvolvinginhibitionoftypeIIglucosetransporter.

    WuCHetal(2009)IntJCancer124(9):2210-9.
    PubMedID:19123483
品牌介绍
Hello Bio是由一群经验丰富的科学家和化学家们创立的充满活力的生物企业,总部位于英国布里斯托尔,在美国普林斯顿设有分公司,主旨在于提供质优价廉的生命科学研究工具,主要产品线为小分子化合物,如激动剂、拮抗剂、抑制剂等,部分产品价格甚至低至其他供应商的50%。热销产品线:酶抑制剂和激动剂ROCK inhibitor Y-27632, PKA inhibitor KT 5720 , adenylyl cyclase activator Forskolin, and novel GRK2/3 inhibitor Cmpd101等。 离子通道调节剂NMDA antagonist D-AP5, sodium channel blocker tetrodotoxin citrate, TRP antagonist capsazepine, and GABAA antagonist SR 95531 等。信号通路工具各种信号通路抑制剂、激动剂表观遗传学研究工具potent HDAC inhibitor Trichostatin A, DNA methyltransferase inhibitor 5-aza-2'-deoxycytidine,BET bromodomain inhibitor (+)-JQ1 and potent,selective GLP / G9a HMTase inhibitor BIX 01294 等受体配体novel selective GRK2/3 inhibitor,  NMDA antagonist D-AP5, Group I mGlu agonist (S)-3,5-DHPG, and GABAA antagonist SR 95531.等干细胞调节剂ROCK inhibitor Y-27632,  SB 431542 DAPT.