Hello Bio/NSC 3852/HB1392/50mg
商品编号：
HB1392-50mg
品牌：
hellobio
市场价：
¥1560.00
美元价：
1200.00
产品分类：
酸碱缓冲液
联系Q Q：
3392242852
电话号码：
4000-520-616
电子邮箱：
info@ebiomall.com
商品介绍
Productoverview
- NameNSC3852
- ShortdescriptionNon-selectiveHDACinhibitor
- BIOLOGicaldescriptionNon-selectivehistonedeacetylase(HDAC)inhibitor.CausesreactiveoxygenspeciesreleaseanddamagesDNA.Showsanti-proliferative,apoptotic,anti-cancerandanti-protozoalactions.
- Alternativenames5-nitroso-8-quinolinol
- BiologicalactionInhibitor
- OurproductsinactionSubmitYourCitationNow
Properties
- Chemicalname5-Nitroso-8-quinolinol
- MolecularWeight174.16
- Chemicalstructure
![NSC 3852 [3565-26-2]](images/hellobio/201710/hb1392.png "NSC 3852 [3565-26-2]")
- MolecularFormulaC9H6N2O2
- CASNumber3565-26-2
StoringandUsingYourProduct
- Storageinstructionsroomtemperature
- SolubilityoverviewsolubleinDMSO(100mM)orethanol(10mM)
- ImportantThisproductisforRESEARCHUSEONLYandisnotintendedfortherapeuticordiagnosticuse.Notforhumanorveterinaryuse.
ReferencesforNSC3852
Differentiation-inducingquinolinesasexperimentalbreastcanceragentsintheMCF-7humanbreastcancercellmodel.
MartirosyanARetal(2004)BiochemPharmacol68(9):1729-38.PubMedID:15450938ActionsofahistonedeacetylaseinhibitorNSC3852(5-nitroso-8-quinolinol)linkreactiveoxygenspeciestocelldifferentiationandapoptosisinMCF-7humanmammarytumorcells.
MartirosyanAetal(2006)JPharmacolExpTher317(2):546-52.PubMedID:16497787InhibitionofToxoplasmagondiiandPlasmodiumfalciparuminfectionsinvitrobyNSC3852,aredoxactiveantiproliferativeandtumorcelldifferentiationagent.
StroblJSetal(2009)JParasitol95(1):215-23.PubMedID:18837587
品牌介绍
Hello Bio是由一群经验丰富的科学家和化学家们创立的充满活力的生物企业，总部位于英国布里斯托尔，在美国普林斯顿设有分公司，主旨在于提供质优价廉的生命科学研究工具，主要产品线为小分子化合物，如激动剂、拮抗剂、抑制剂等，部分产品价格甚至低至其他供应商的50%。热销产品线：酶抑制剂和激动剂ROCK inhibitor Y-27632, PKA inhibitor KT 5720 , adenylyl cyclase activator Forskolin, and novel GRK2/3 inhibitor Cmpd101等。 离子通道调节剂NMDA antagonist D-AP5, sodium channel blocker tetrodotoxin citrate, TRP antagonist capsazepine, and GABAA antagonist SR 95531 等。信号通路工具各种信号通路抑制剂、激动剂表观遗传学研究工具potent HDAC inhibitor Trichostatin A, DNA methyltransferase inhibitor 5-aza-2'-deoxycytidine,BET bromodomain inhibitor (+)-JQ1 and potent,selective GLP / G9a HMTase inhibitor BIX 01294 等受体配体novel selective GRK2/3 inhibitor, NMDA antagonist D-AP5, Group I mGlu agonist (S)-3,5-DHPG, and GABAA antagonist SR 95531.等干细胞调节剂ROCK inhibitor Y-27632, SB 431542 DAPT.
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