Hello Bio/Naspm trihydrochloride/HB0441/25mg
商品编号：
HB0441-5mg
品牌：
hellobio
市场价：
¥1189.50
美元价：
915.00
产品分类：
酸碱缓冲液
联系Q Q：
3392242852
电话号码：
4000-520-616
电子邮箱：
info@ebiomall.com
商品介绍
Productoverview
- NameNaspmtrihydrochloride
- ShortdescriptionSelectiveGluA2-lacking,Ca2+permeableAMPA/kainatereceptorantagoNIST
- BIOLOGicaldescriptionSelectiveGluA2-lacking,Ca2+permeableAMPA/kainatereceptorantagonist.SyntheticanalogueofJorospidertoxin.Reducesexcitatorypostsynapticcurrentsininfralimbicneurons.
- BiologicalactionAntagonist
- Purity>97%
- OurproductsinactionSubmitYourCitationNow
Properties
- ChemicalnameN-[3-[[4-[(3-Aminopropyl)amino]butyl]amino]propyl]-1-naphthaleneacetamidetrihydrochloride
- MolecularWeight479.91
- Chemicalstructure
![Naspm trihydrochloride [1049731-36-3]](images/hellobio/201710/hb0441.png "Naspm trihydrochloride [1049731-36-3]")
- MolecularFormulaC22H34N4O.3HCl
- CASNumber1049731-36-3
- PubChemidentifier16219727
- SMILESC1=CC=C2C(=C1)C=CC=C2CC(=O)NCCCNCCCCNCCCN.Cl.Cl.Cl
- InChiInChI=1S/C22H34N4O.3ClH/c23-12-6-15-24-13-3-4-14-25-16-7-17-26-22(27)18-20-10-5-9-19-8-1-2-11-21(19)20;;;/h1-2,5,8-11,24-25H,3-4,6-7,12-18,23H2,(H,26,27);3*1H
- InChiKeyJNEOJAUJWOPWJS-UHFFFAOYSA-N
- MDLnumberMFCD01321052
StoringandUsingYourProduct
- Storageinstructions+4°C(desiccate)
- SolubilityoverviewSolubleinwater(100mM)
- ImportantThisproductisforRESEARCHUSEONLYandisnotintendedfortherapeuticordiagnosticuse.Notforhumanorveterinaryuse.
ReferencesforNaspmtrihydrochloride
Blockingeffectof1-naphthylacetylspermineonCa(2+)-permeableAMPAreceptorsinculturedrathippocampalneurons.
KoikeMetal(1997)NeurosciRes29(1):27-36.PubMedID:9293490ABArenewalinvolvesenhancementsinbothGluA2-lackingAMPAreceptoractivityandGluA1phosphorylationinthelateralamygdala.
ParkKetal(2014)PLoSOne9(6):e100108.PubMedID:24925360FearextinctioninducesmGluR5-mediatedsynapticandintrinsicplasticityininfralimbicneurons.
Sepulveda-OrengoMTetal(2013)JNeurosci33(17):7184-93.PubMedID:23616528
品牌介绍
Hello Bio是由一群经验丰富的科学家和化学家们创立的充满活力的生物企业，总部位于英国布里斯托尔，在美国普林斯顿设有分公司，主旨在于提供质优价廉的生命科学研究工具，主要产品线为小分子化合物，如激动剂、拮抗剂、抑制剂等，部分产品价格甚至低至其他供应商的50%。热销产品线：酶抑制剂和激动剂ROCK inhibitor Y-27632, PKA inhibitor KT 5720 , adenylyl cyclase activator Forskolin, and novel GRK2/3 inhibitor Cmpd101等。 离子通道调节剂NMDA antagonist D-AP5, sodium channel blocker tetrodotoxin citrate, TRP antagonist capsazepine, and GABAA antagonist SR 95531 等。信号通路工具各种信号通路抑制剂、激动剂表观遗传学研究工具potent HDAC inhibitor Trichostatin A, DNA methyltransferase inhibitor 5-aza-2'-deoxycytidine,BET bromodomain inhibitor (+)-JQ1 and potent,selective GLP / G9a HMTase inhibitor BIX 01294 等受体配体novel selective GRK2/3 inhibitor, NMDA antagonist D-AP5, Group I mGlu agonist (S)-3,5-DHPG, and GABAA antagonist SR 95531.等干细胞调节剂ROCK inhibitor Y-27632, SB 431542 DAPT.
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