你好Bio/N-花生四烯基-L-丙氨酸/HB0440/25mg
商品编号：
HB0440-25mg
品牌：
hellobio
市场价：
¥4602.00
美元价：
3540.00
产品分类：
酸碱缓冲液
联系Q Q：
3392242852
电话号码：
4000-520-616
电子邮箱：
info@ebiomall.com
商品介绍
Product overview
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NameN-Arachidonyl-L-alanine
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Short descriptionGLYT2 / GLYT2(EL2) inhibitor
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Biological descriptionGLYT2 and GLYT2(EL2) inhibitor (IC30 values are 5.9 and 6.0 µM). Displays little or no activity at GLYT1 (IC30 = >30 µM). Inhibits pain.
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Biological actionInhibitor
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Purity>98%
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Properties
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Chemical name2-(Icosa-5,8,11,14-tetraenoylamino)propanoic acid
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Molecular Weight375.6
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Chemical structure
![N-Arachidonyl-L-alanine [401941-73-9]](images/hellobio/201710/hb0440.png "N-Arachidonyl-L-alanine [401941-73-9]")
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Molecular FormulaC23H37NO3
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CAS Number401941-73-9
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PubChem identifier53394356
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SMILESC[C@@H](NC(=O)CCC/C=CC/C=CC/C=CC/C=CCCCCC)C(=O)O
Storing and Using Your Product
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Storage instructions-20°C (desiccate)
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Solubility overviewsoluble in DMSO (50mM) or ethanol (50mM)
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ImportantThis product is for RESEARCH USE ONLY and is not intended for therapeutic or diagnostic use. Not for human or veterinary use.
References for N-Arachidonyl-L-alanine
Extracellular loops 2 and 4 of GLYT2 are required for N-arachidonylglycine inhibition of glycine transport.
Edington AR et al (2009) J Biol Chem 284(52) : 36424-30.PubMedID: 19875446Identification of a new class of molecules, the arachidonyl amino acids, and characterization of one member that inhibits pain.
Huang SM et al (2001) J Biol Chem 276(46) : 42639-44.PubMedID: 11518719
品牌介绍
Hello Bio是由一群经验丰富的科学家和化学家们创立的充满活力的生物企业，总部位于英国布里斯托尔，在美国普林斯顿设有分公司，主旨在于提供质优价廉的生命科学研究工具，主要产品线为小分子化合物，如激动剂、拮抗剂、抑制剂等，部分产品价格甚至低至其他供应商的50%。热销产品线：酶抑制剂和激动剂ROCK inhibitor Y-27632, PKA inhibitor KT 5720 , adenylyl cyclase activator Forskolin, and novel GRK2/3 inhibitor Cmpd101等。 离子通道调节剂NMDA antagonist D-AP5, sodium channel blocker tetrodotoxin citrate, TRP antagonist capsazepine, and GABAA antagonist SR 95531 等。信号通路工具各种信号通路抑制剂、激动剂表观遗传学研究工具potent HDAC inhibitor Trichostatin A, DNA methyltransferase inhibitor 5-aza-2'-deoxycytidine,BET bromodomain inhibitor (+)-JQ1 and potent,selective GLP / G9a HMTase inhibitor BIX 01294 等受体配体novel selective GRK2/3 inhibitor, NMDA antagonist D-AP5, Group I mGlu agonist (S)-3,5-DHPG, and GABAA antagonist SR 95531.等干细胞调节剂ROCK inhibitor Y-27632, SB 431542 DAPT.
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