Hello Bio/L-NAME/HB1352/5g
市场价：
¥1014.00
美元价：
780.00
产品分类：
酸碱缓冲液
联系Q Q：
3392242852
电话号码：
4000-520-616
电子邮箱：
info@ebiomall.com
商品介绍
Productoverview
- NameL-NAME
- ShortdescriptionNon-selectiveNOSinhibitor
- BIOLOGicaldescriptionNon-selectivenitricoxidesynthase(NOS)inhibitor.AlsoinhibitscyclicGMP(IC50=3.1μM).Methylesterpro-drugofL-NNA.Displayshypertensiveproperties.
- BiologicalactionInhibitor
- Purity>98%
- OurproductsinactionSubmitYourCitationNow
Properties
- ChemicalnameNomega-Nitro-L-argininemethylesterhydrochloride
- MolecularWeight269.69
- Chemicalstructure
![L-NAME [51298-62-5]](images/hellobio/201710/hb1352.png "L-NAME [51298-62-5]")
- MolecularFormulaC7H15N5O4.HCl
- CASNumber51298-62-5
- PubChemidentifier135193
- SMILESCOC(=O)[C@H](CCCN=C(N)N[N+](=O)[O-])N.Cl
- InChiInChI=1S/C7H15N5O4.ClH/c1-16-6(13)5(8)3-2-4-10-7(9)11-12(14)15;/h5H,2-4,8H2,1H3,(H3,9,10,11);1H/t5-;/m0./s1
- InChiKeyQBNXAGZYLSRPJK-JEDNCBNOSA-N
- MDLnumberMFCD00039052
StoringandUsingYourProduct
- StorageinstructionsRoomtemperature
- SolubilityoverviewSolubleinwater(100mM)
- ImportantThisproductisforRESEARCHUSEONLYandisnotintendedfortherapeuticordiagnosticuse.Notforhumanorveterinaryuse.
ReferencesforL-NAME
L-NAMEinthecardiovascularsystem-nitricoxidesynthaseactivator?
KopincováJetal(2012)PharmacolRep64(3):511-20.PubMedID:22814004Nitricoxidesynthases:structure,functionandinhibition.
AldertonWKetal(2001)BiochemJ357(Pt3):593-615.PubMedID:11463332Characterizationofthreeinhibitorsofendothelialnitricoxidesynthaseinvitroandinvivo.
ReesDDetal(1990)BrJPharmacol101(3):746-52.PubMedID:1706208
品牌介绍
Hello Bio是由一群经验丰富的科学家和化学家们创立的充满活力的生物企业，总部位于英国布里斯托尔，在美国普林斯顿设有分公司，主旨在于提供质优价廉的生命科学研究工具，主要产品线为小分子化合物，如激动剂、拮抗剂、抑制剂等，部分产品价格甚至低至其他供应商的50%。热销产品线：酶抑制剂和激动剂ROCK inhibitor Y-27632, PKA inhibitor KT 5720 , adenylyl cyclase activator Forskolin, and novel GRK2/3 inhibitor Cmpd101等。 离子通道调节剂NMDA antagonist D-AP5, sodium channel blocker tetrodotoxin citrate, TRP antagonist capsazepine, and GABAA antagonist SR 95531 等。信号通路工具各种信号通路抑制剂、激动剂表观遗传学研究工具potent HDAC inhibitor Trichostatin A, DNA methyltransferase inhibitor 5-aza-2'-deoxycytidine,BET bromodomain inhibitor (+)-JQ1 and potent,selective GLP / G9a HMTase inhibitor BIX 01294 等受体配体novel selective GRK2/3 inhibitor, NMDA antagonist D-AP5, Group I mGlu agonist (S)-3,5-DHPG, and GABAA antagonist SR 95531.等干细胞调节剂ROCK inhibitor Y-27632, SB 431542 DAPT.
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