
Hello Bio/MNI-caged-L-Glutamate/HB0423/50mg
商品编号:
HB0423-50mg
品牌:
hellobio
市场价:
¥5889.00
美元价:
4530.00
产品分类:
酸碱缓冲液
联系Q Q:
3392242852
电话号码:
4000-520-616
电子邮箱:
info@ebiomall.com
商品介绍
Product overview
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NameMNI-caged-L-Glutamate
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Short descriptionCaged glutamate that rapidly and efficiently releases glutamate when photolysed
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Biological description
Caged glutamate that rapidly and efficiently releases glutamate when photolysed (300 - 380 nm excitation).
Inactive at glutamate receptors and transporters at mM concentrations.
Water soluble, resistant to hydrolysis and stable at neutral pH.
Not currently for sale in the USA. -
Alternative namesMNI-Glu, Caged glutamate, MNI-Glutamate,
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Biological actionActivator
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Purity>98%
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Customer comments
We confirmed Hello Bio MNI-caged-glutamate works very well for our two-photon uncaging experiment. I would be very happy to recommend your MNI glutamate. Verified customer
We are very pleased to have such a company like yours that offers products like MNI-Glu at a very good price and still with a high quality. So we will rate your product 5 stars! Verified customer, LIN, Magdeburg
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Our products in actionSubmit Your Citation Now
Images
Properties
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Chemical name(S)-α-Amino-2,3-dihydro-4-methoxy-7-nitro-δ-oxo-1H-indole-1-pentanoic acid
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Molecular Weight323.3
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Chemical structure
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Molecular FormulaC14H17N3O6
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CAS Number295325-62-1
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PubChem identifier6604871
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SMILESCOC1=C2CCN(C2=C(C=C1)[N+](=O)[O-])C(=O)CC[C@@H](C(=O)O)N
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SourceSynthetic
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InChi1S/C14H17N3O6/c1-23-11-4-3-10(17(21)22)13-8(11)6-7-16(13)12(18)5-2-9(15)14(19)20/h3-4,9H,2,5-7,15H2,1H3,(H,19,20)/t9-/m0/s1
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InChiKeyGXIDBZKXGUNITQ-VIFPVBQESA-N
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AppearanceYellow solid
Storing and Using Your Product
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Storage instructions-20 °C
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Solubility overviewSoluble in water (50mM) with gentle warming
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HandlingThis compound is light sensitive; exposure to light may affect compound performance. We therefore recommend storing the material in the dark and protecting from light.
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ImportantThis product is for RESEARCH USE ONLY and is not intended for therapeutic or diagnostic use. Not for human or veterinary use.
References for MNI-caged-L-Glutamate
Photochemical and pharmacological evaluation of 7-nitroindolinyl-and 4-methoxy-7-nitroindolinyl-amino acids as novel, fast caged neurotransmitters.
Canepari et al (2001) J Neurosci Methods 112(1) : 29-42PubMedID: 11640955Comparative analysis of inhibitory effects of caged ligands for the NMDA receptor.
Maier et al (2005) J Neurosci Methods 142(1) : 1-9PubMedID: 15652611New caged neurotransmitter analogs selective for glutamate receptor sub-types based on methoxynitroindoline and nitrophenylethoxycarbonyl caging groups.
Palma-Cerda et al (2012) Neuropharmacology 63(4) : 624-34PubMedID: 22609535
品牌介绍
Hello Bio是由一群经验丰富的科学家和化学家们创立的充满活力的生物企业,总部位于英国布里斯托尔,在美国普林斯顿设有分公司,主旨在于提供质优价廉的生命科学研究工具,主要产品线为小分子化合物,如激动剂、拮抗剂、抑制剂等,部分产品价格甚至低至其他供应商的50%。热销产品线:酶抑制剂和激动剂ROCK inhibitor Y-27632, PKA inhibitor KT 5720 , adenylyl cyclase activator Forskolin, and novel GRK2/3 inhibitor Cmpd101等。 离子通道调节剂NMDA antagonist D-AP5, sodium channel blocker tetrodotoxin citrate, TRP antagonist capsazepine, and GABAA antagonist SR 95531 等。信号通路工具各种信号通路抑制剂、激动剂表观遗传学研究工具potent HDAC inhibitor Trichostatin A, DNA methyltransferase inhibitor 5-aza-2'-deoxycytidine,BET bromodomain inhibitor (+)-JQ1 and potent,selective GLP / G9a HMTase inhibitor BIX 01294 等受体配体novel selective GRK2/3 inhibitor, NMDA antagonist D-AP5, Group I mGlu agonist (S)-3,5-DHPG, and GABAA antagonist SR 95531.等干细胞调节剂ROCK inhibitor Y-27632, SB 431542 DAPT.
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