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当前位置: 首页 > 产品中心 > acid_base_buffer_solution > Hello Bio/MNI-caged-L-Glutamate/HB0423/50mg
商品详细Hello Bio/MNI-caged-L-Glutamate/HB0423/50mg
Hello Bio/MNI-caged-L-Glutamate/HB0423/50mg
Hello Bio/MNI-caged-L-Glutamate/HB0423/50mg
商品编号: HB0423-50mg
品牌: hellobio
市场价: ¥5889.00
美元价: 4530.00
产地: 美国(厂家直采)
公司:
产品分类: 酸碱缓冲液
公司分类: acid_base_buffer_solution
联系Q Q: 3392242852
电话号码: 4000-520-616
电子邮箱: info@ebiomall.com
商品介绍

Product overview

  • Name
    MNI-caged-L-Glutamate
  • Short description
    Caged glutamate that rapidly and efficiently releases glutamate when photolysed
  • Biological description

    Caged glutamate that rapidly and efficiently releases glutamate when photolysed (300 - 380 nm excitation).

    Inactive at glutamate receptors and transporters at mM concentrations.

    Water soluble, resistant to hydrolysis and stable at neutral pH.


    Not currently for sale in the USA.

  • Alternative names
    MNI-Glu, Caged glutamate, MNI-Glutamate,
  • Biological action
    Activator
  • Purity
    >98%
  • Customer comments

    We confirmed Hello Bio MNI-caged-glutamate works very well for our two-photon uncaging experiment. I would be very happy to recommend your MNI glutamate. Verified customer

    We are very pleased to have such a company like yours that offers products like MNI-Glu at a very good price and still with a high quality. So we will rate your product 5 stars! Verified customer, LIN, Magdeburg

  • Our products in action
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Images

Properties

  • Chemical name
    (S)-α-Amino-2,3-dihydro-4-methoxy-7-nitro-δ-oxo-1H-indole-1-pentanoic acid
  • Molecular Weight
    323.3
  • Chemical structure
    MNI-glutamate [295325-62-1]
  • Molecular Formula
    C14H17N3O6
  • CAS Number
    295325-62-1
  • PubChem identifier
    6604871
  • SMILES
    COC1=C2CCN(C2=C(C=C1)[N+](=O)[O-])C(=O)CC[C@@H](C(=O)O)N
  • Source
    Synthetic
  • InChi
    1S/C14H17N3O6/c1-23-11-4-3-10(17(21)22)13-8(11)6-7-16(13)12(18)5-2-9(15)14(19)20/h3-4,9H,2,5-7,15H2,1H3,(H,19,20)/t9-/m0/s1
  • InChiKey
    GXIDBZKXGUNITQ-VIFPVBQESA-N
  • Appearance
    Yellow solid

Storing and Using Your Product

  • Storage instructions
    -20 °C
  • Solubility overview
    Soluble in water (50mM) with gentle warming
  • Handling
    This compound is light sensitive; exposure to light may affect compound performance. We therefore recommend storing the material in the dark and protecting from light.
  • Important
    This product is for RESEARCH USE ONLY and is not intended for therapeutic or diagnostic use. Not for human or veterinary use.

References for MNI-caged-L-Glutamate

  • Photochemical and pharmacological evaluation of 7-nitroindolinyl-and 4-methoxy-7-nitroindolinyl-amino acids as novel, fast caged neurotransmitters.

    Canepari et al (2001) J Neurosci Methods 112(1) : 29-42
    PubMedID: 11640955
  • Comparative analysis of inhibitory effects of caged ligands for the NMDA receptor.

    Maier et al (2005) J Neurosci Methods 142(1) : 1-9
    PubMedID: 15652611
  • New caged neurotransmitter analogs selective for glutamate receptor sub-types based on methoxynitroindoline and nitrophenylethoxycarbonyl caging groups.

    Palma-Cerda et al (2012) Neuropharmacology 63(4) : 624-34
    PubMedID: 22609535
品牌介绍
Hello Bio是由一群经验丰富的科学家和化学家们创立的充满活力的生物企业,总部位于英国布里斯托尔,在美国普林斯顿设有分公司,主旨在于提供质优价廉的生命科学研究工具,主要产品线为小分子化合物,如激动剂、拮抗剂、抑制剂等,部分产品价格甚至低至其他供应商的50%。热销产品线:酶抑制剂和激动剂ROCK inhibitor Y-27632, PKA inhibitor KT 5720 , adenylyl cyclase activator Forskolin, and novel GRK2/3 inhibitor Cmpd101等。 离子通道调节剂NMDA antagonist D-AP5, sodium channel blocker tetrodotoxin citrate, TRP antagonist capsazepine, and GABAA antagonist SR 95531 等。信号通路工具各种信号通路抑制剂、激动剂表观遗传学研究工具potent HDAC inhibitor Trichostatin A, DNA methyltransferase inhibitor 5-aza-2'-deoxycytidine,BET bromodomain inhibitor (+)-JQ1 and potent,selective GLP / G9a HMTase inhibitor BIX 01294 等受体配体novel selective GRK2/3 inhibitor,  NMDA antagonist D-AP5, Group I mGlu agonist (S)-3,5-DHPG, and GABAA antagonist SR 95531.等干细胞调节剂ROCK inhibitor Y-27632,  SB 431542 DAPT.