Hello Bio/MMPX/HB0092/50mg
商品编号：
HB0092-50mg
品牌：
hellobio
市场价：
¥14293.50
美元价：
10995.00
产品分类：
酸碱缓冲液
联系Q Q：
3392242852
电话号码：
4000-520-616
电子邮箱：
info@ebiomall.com
商品介绍
Productoverview
- NameMMPX
- ShortdescriptionSelectivecalmodulin-dependentPDE-1inhibitor
- BIOLOGicaldescriptionSelectivecalmodulin-dependentphosphodiesterase1(PDE-1)inhibitor.IncreasesCa2+-activatedK+(BK)channelactivityintheurinarybladderandshowssmoothmusclerelaxingactions.Alsoshowsvasodilatoractions.
- Alternativenames8-Methoxymethyl-IBMX
- BiologicalactionInhibitor
- Purity>98%
- OurproductsinactionSubmitYourCitationNow
Properties
- MolecularWeight266.3
- Chemicalstructure
![8-Methoxymethyl-IBMX [78033-08-6]](images/hellobio/201710/hb0092.png "8-Methoxymethyl-IBMX [78033-08-6]")
- MolecularFormulaC12H18N4O3
- CASNumber78033-08-6
- PubChemidentifier155806
- SMILESCC(C)CN1C2=C(C(=O)N(C1=O)C)NC(=N2)COC
StoringandUsingYourProduct
- Storageinstructionsroomtemperature
- SolubilityoverviewsolubleinethanolorDMOS(5mg/ml)
- ImportantThisproductisforRESEARCHUSEONLYandisnotintendedfortherapeuticordiagnosticuse.Notforhumanorveterinaryuse.
ReferencesforMMPX
Effectsofselectiveinhibitorsoncyclicnucleotidephosphodiesterasesofrabbitaorta.
AhnHSetal(1989)BiochemPharmacol38(19):3331-9.PubMedID:2554921Selectiveinhibitionofphosphodiesterase1relaxesurinarybladdersmoothmuscle:roleforryanodinereceptor-mediatedBKchannelactivation.
XinWetal(2012)AmJPhysiolCellPhysiol303(10):C1079-89.PubMedID:22992675Invivoeffectsofphosphodiesteraseinhibitiononbasalcyclicguanosinemonophosphatelevelsintheprefrontalcortex,hippocampusandcerebellumoffreelymovingrats.
MarteAetal(2008)JNeurosciRes86(15):3338-47.PubMedID:18655195Lungvasodilatoryresponsetoinhalediloprostinexperimentalpulmonaryhypertension:amplificationbydifferenttypephosphodiesteraseinhibitors.
SchermulyRTetal(2005)RespirRes6:76PubMedID:16033645
品牌介绍
Hello Bio是由一群经验丰富的科学家和化学家们创立的充满活力的生物企业，总部位于英国布里斯托尔，在美国普林斯顿设有分公司，主旨在于提供质优价廉的生命科学研究工具，主要产品线为小分子化合物，如激动剂、拮抗剂、抑制剂等，部分产品价格甚至低至其他供应商的50%。热销产品线：酶抑制剂和激动剂ROCK inhibitor Y-27632, PKA inhibitor KT 5720 , adenylyl cyclase activator Forskolin, and novel GRK2/3 inhibitor Cmpd101等。 离子通道调节剂NMDA antagonist D-AP5, sodium channel blocker tetrodotoxin citrate, TRP antagonist capsazepine, and GABAA antagonist SR 95531 等。信号通路工具各种信号通路抑制剂、激动剂表观遗传学研究工具potent HDAC inhibitor Trichostatin A, DNA methyltransferase inhibitor 5-aza-2'-deoxycytidine,BET bromodomain inhibitor (+)-JQ1 and potent,selective GLP / G9a HMTase inhibitor BIX 01294 等受体配体novel selective GRK2/3 inhibitor, NMDA antagonist D-AP5, Group I mGlu agonist (S)-3,5-DHPG, and GABAA antagonist SR 95531.等干细胞调节剂ROCK inhibitor Y-27632, SB 431542 DAPT.
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