Hello Bio/Mifepristone/HB2783/100mg
商品编号：
HB2783-100mg
品牌：
hellobio
市场价：
¥1053.00
美元价：
810.00
产品分类：
酸碱缓冲液
联系Q Q：
3392242852
电话号码：
4000-520-616
电子邮箱：
info@ebiomall.com
商品介绍
Productoverview
- NameMifepristone
- ShortdescriptionPotentglucocorticoidandprogesteronereceptorantagoNIST
- BIOLOGicaldescriptionPotentglucocorticoid(GR)andprogesteronereceptor(PR)antagonist(EC50valuesare2,10.6and9.5nMatGR,PR-AandPR-Brespectively).Alsoweaklybindstheandrogenreceptor.ShowshigheraffinityforPRsthanprogesterone.Showsneuroprotectiveandantitumoreffects.Activeinvivo.
- AlternativenamesRU486|RU38486
- BiologicalactionAntagonist
- Purity>99%
- OurproductsinactionSubmitYourCitationNow
Properties
- Chemicalname(11β,17β)-11-[4-(Dimethylamino)phenyl]-17-hydroxy-17-(1-propynyl)-estra-4,9-dien-3-one
- MolecularWeight429.6
- Chemicalstructure
- MolecularFormulaC29H35NO2
- CASNumber84371-65-3
StoringandUsingYourProduct
- Storageinstructionsroomtemperature
- ImportantThisproductisforRESEARCHUSEONLYandisnotintendedfortherapeuticordiagnosticuse.Notforhumanorveterinaryuse.
ReferencesforMifepristone
Mifepristonepreventsstress-inducedapoptosisinnewbornneuronsandincreasesAMPAreceptorexpressioninthedentategyrusofC57/BL6mice.
Llorens-Martã?nMetal(2011)PLoSOne6(11):e28376.PubMedID:22140582ThechemopreventiveeffectofmifepristoneonmammarytumOrigenesisisassociatedwithananti-invasiveandanti-inflammatorygenesignature.
YuanHetal(2012)CancerPrevRes(Phila)5(5):754-64.PubMedID:22427346NovelprotectiveeffectofmifepristoneondetrimentalGABAAreceptoractivitytoimmaturePurkinjeneurons.
RakotomamonjyJetal(2011)FASEBJ25(11):3999-4010.PubMedID:21795502Bindingoftheanti-progestinRU-486toratovarysteroidreceptors.
SchreiberJRetal(1983)Contraception28(1):77-85.PubMedID:6627946
品牌介绍
Hello Bio是由一群经验丰富的科学家和化学家们创立的充满活力的生物企业，总部位于英国布里斯托尔，在美国普林斯顿设有分公司，主旨在于提供质优价廉的生命科学研究工具，主要产品线为小分子化合物，如激动剂、拮抗剂、抑制剂等，部分产品价格甚至低至其他供应商的50%。热销产品线：酶抑制剂和激动剂ROCK inhibitor Y-27632, PKA inhibitor KT 5720 , adenylyl cyclase activator Forskolin, and novel GRK2/3 inhibitor Cmpd101等。 离子通道调节剂NMDA antagonist D-AP5, sodium channel blocker tetrodotoxin citrate, TRP antagonist capsazepine, and GABAA antagonist SR 95531 等。信号通路工具各种信号通路抑制剂、激动剂表观遗传学研究工具potent HDAC inhibitor Trichostatin A, DNA methyltransferase inhibitor 5-aza-2'-deoxycytidine,BET bromodomain inhibitor (+)-JQ1 and potent,selective GLP / G9a HMTase inhibitor BIX 01294 等受体配体novel selective GRK2/3 inhibitor, NMDA antagonist D-AP5, Group I mGlu agonist (S)-3,5-DHPG, and GABAA antagonist SR 95531.等干细胞调节剂ROCK inhibitor Y-27632, SB 431542 DAPT.
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