Hello Bio/(R,S)-MCPG sodium salt/HB0038/
市场价：
¥1482.00
美元价：
1140.00
产品分类：
酸碱缓冲液
联系Q Q：
3392242852
电话号码：
4000-520-616
电子邮箱：
info@ebiomall.com
商品介绍
Productoverview
- Name(R,S)-MCPGsodiumsalt
- ShortdescriptionWatersoluble,non-selectivegroupIandIImGluRantagoNIST
- BIOLOGicaldescription
Watersolublenon-selectivegroupIandIImGluRantagonist.
AlsocompetitiveantagonistofACPDsensitivereceptors.
Showsnoeffectonlocomotoractivity.
(R,S)-MCPGand(S)-MCPGsodiumsaltalsoavailable.(S)-MCPGalsoavailable.
- BiologicalactionAntagonist
- Purity>98%
- OurproductsinactionSubmitYourCitationNow
Properties
- Chemicalname(RS)-α-Methyl-4-carboxyphenylglycinedisodiumsalt
- MolecularWeight253.16
- Chemicalstructure
![(R,S)-MCPG sodium salt [1303994-09-3]](images/hellobio/201710/hb0038.png "(R,S)-MCPG sodium salt [1303994-09-3]")
- MolecularFormulaC10H9NNa2O4
- CASNumber1303994-09-3
- SMILESNC(C)(C(=O)O[Na])c1ccc(cc1)C(=O)O
- SourceSynthetic
- AppearanceWhitesolid
StoringandUsingYourProduct
- StorageinstructionsRoomtemperature
- SolubilityoverviewSolubleinwater(100mM)
- ImportantThisproductisforRESEARCHUSEONLYandisnotintendedfortherapeuticordiagnosticuse.Notforhumanorveterinaryuse.
Referencesfor(R,S)-MCPGsodiumsalt
Themetabotropicglutamatereceptorantagonist(RS)-MCPGproduceshyperlocomotioninamphetaminepre-exposedrats.
KimJHetal(1998)Neuropharmacology37(2):189-97.PubMedID:9680243MCPGantagonizesmetabotropicglutamatereceptorsbutnotlong-termpotentiationinthehippocampus.
ManzoniOJetal(1994)EurJNeurosci6(6):1050-4.PubMedID:7952274Competitiveantagonismatmetabotropicglutamatereceptorsby(S)-4-carboxyphenylglycineand(RS)-alpha-methyl-4-carboxyphenylglycine.
EatonSAetal(1993)EurJPharmacol244(2):195-7.PubMedID:8381746
品牌介绍
Hello Bio是由一群经验丰富的科学家和化学家们创立的充满活力的生物企业，总部位于英国布里斯托尔，在美国普林斯顿设有分公司，主旨在于提供质优价廉的生命科学研究工具，主要产品线为小分子化合物，如激动剂、拮抗剂、抑制剂等，部分产品价格甚至低至其他供应商的50%。热销产品线：酶抑制剂和激动剂ROCK inhibitor Y-27632, PKA inhibitor KT 5720 , adenylyl cyclase activator Forskolin, and novel GRK2/3 inhibitor Cmpd101等。 离子通道调节剂NMDA antagonist D-AP5, sodium channel blocker tetrodotoxin citrate, TRP antagonist capsazepine, and GABAA antagonist SR 95531 等。信号通路工具各种信号通路抑制剂、激动剂表观遗传学研究工具potent HDAC inhibitor Trichostatin A, DNA methyltransferase inhibitor 5-aza-2'-deoxycytidine,BET bromodomain inhibitor (+)-JQ1 and potent,selective GLP / G9a HMTase inhibitor BIX 01294 等受体配体novel selective GRK2/3 inhibitor, NMDA antagonist D-AP5, Group I mGlu agonist (S)-3,5-DHPG, and GABAA antagonist SR 95531.等干细胞调节剂ROCK inhibitor Y-27632, SB 431542 DAPT.
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