Hello Bio/(R,S)-MCPG sodium salt/HB0038/50mg
商品编号：
HB0038-50mg
品牌：
hellobio
市场价：
¥4524.00
美元价：
3480.00
产品分类：
酸碱缓冲液
联系Q Q：
3392242852
电话号码：
4000-520-616
电子邮箱：
info@ebiomall.com
商品介绍
Product overview
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Name(R,S)-MCPG sodium salt
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Short descriptionWater soluble, non-selective group I and II mGluR antagonist
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Biological description
Water soluble non-selective group I and II mGluR antagonist.
Also competitive antagonist of ACPD sensitive receptors.
Shows no effect on locomotor activity.
(R,S)-MCPG and (S)-MCPG sodium salt also available. (S)-MCPG also available.
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Biological actionAntagonist
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Purity>98%
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Properties
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Chemical name(RS)-α-Methyl-4-carboxyphenylglycine disodium salt
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Molecular Weight253.16
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Chemical structure
![(R,S)-MCPG sodium salt [1303994-09-3]](images/hellobio/201710/hb0038.png "(R,S)-MCPG sodium salt [1303994-09-3]")
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Molecular FormulaC10H9NNa2O4
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CAS Number1303994-09-3
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SMILESNC(C)(C(=O)O[Na])c1ccc(cc1)C(=O)O
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SourceSynthetic
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AppearanceWhite solid
Storing and Using Your Product
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Storage instructionsRoom temperature
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Solubility overviewSoluble in water (100mM)
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ImportantThis product is for RESEARCH USE ONLY and is not intended for therapeutic or diagnostic use. Not for human or veterinary use.
References for (R,S)-MCPG sodium salt
The metabotropic glutamate receptor antagonist (RS)-MCPG produces hyperlocomotion in amphetamine pre-exposed rats.
Kim JH et al (1998) Neuropharmacology 37(2) : 189-97.PubMedID: 9680243MCPG antagonizes metabotropic glutamate receptors but not long-term potentiation in the hippocampus.
Manzoni OJ et al (1994) Eur J Neurosci 6(6) : 1050-4.PubMedID: 7952274Competitive antagonism at metabotropic glutamate receptors by (S)-4-carboxyphenylglycine and (RS)-alpha-methyl-4-carboxyphenylglycine.
Eaton SA et al (1993) Eur J Pharmacol 244(2) : 195-7.PubMedID: 8381746
品牌介绍
Hello Bio是由一群经验丰富的科学家和化学家们创立的充满活力的生物企业，总部位于英国布里斯托尔，在美国普林斯顿设有分公司，主旨在于提供质优价廉的生命科学研究工具，主要产品线为小分子化合物，如激动剂、拮抗剂、抑制剂等，部分产品价格甚至低至其他供应商的50%。热销产品线：酶抑制剂和激动剂ROCK inhibitor Y-27632, PKA inhibitor KT 5720 , adenylyl cyclase activator Forskolin, and novel GRK2/3 inhibitor Cmpd101等。 离子通道调节剂NMDA antagonist D-AP5, sodium channel blocker tetrodotoxin citrate, TRP antagonist capsazepine, and GABAA antagonist SR 95531 等。信号通路工具各种信号通路抑制剂、激动剂表观遗传学研究工具potent HDAC inhibitor Trichostatin A, DNA methyltransferase inhibitor 5-aza-2'-deoxycytidine,BET bromodomain inhibitor (+)-JQ1 and potent,selective GLP / G9a HMTase inhibitor BIX 01294 等受体配体novel selective GRK2/3 inhibitor, NMDA antagonist D-AP5, Group I mGlu agonist (S)-3,5-DHPG, and GABAA antagonist SR 95531.等干细胞调节剂ROCK inhibitor Y-27632, SB 431542 DAPT.
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