Hello Bio/(S)-MCPG/HB0056/
市场价：
¥1482.00
美元价：
1140.00
产品分类：
酸碱缓冲液
联系Q Q：
3392242852
电话号码：
4000-520-616
电子邮箱：
info@ebiomall.com
商品介绍
Product overview
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Name(S)-MCPG
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Short descriptionNon-selective group I/II mGluR antagonist
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Biological description
Non-selective group I and II mGluR antagonist. Water soluble sodium salt.
Active enantiomer of (R,S)-MCPG.
Displays slight activity at mGlu8 receptor but none at mGlu4 receptor.Inhibits MF-LTP (mossy fiber long term potentiation) and blocks induction of LTP in CA1 of rat hippocampus.
Water soluble (R,S)-MCPG sodium salt and (S)-MCPG sodium salt also available. -
Alternative names(S)-M4CPG
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Biological actionAntagonist
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Purity>99%
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Our products in actionSubmit Your Citation Now
Properties
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Chemical name(S)-α-Methyl-4-carboxyphenylglycine
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Molecular Weight209.2
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Chemical structure
![(S)-MCPG [150145-89-4]](images/hellobio/201710/hb0056.png "(S)-MCPG [150145-89-4]")
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Molecular FormulaC10H11NO4
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CAS Number150145-89-4
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PubChem identifier446355
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SMILESC[C@](C1=CC=C(C=C1)C(=O)O)(C(=O)O)N
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SourceSynthetic
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InChiInChI=1S/C10H11NO4/c1-10(11,9(14)15)7-4-2-6(3-5-7)8(12)13/h4-5H,11H2,1H3,(H,12,13)(H,14,15)/t10-/m0/s1
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InChiKeyDNCAZYRLRMTVSF-JTQLQIEISA-N
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MDL numberMFCD00216858
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AppearanceWhite solid
Storing and Using Your Product
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Storage instructionsRoom temperature
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Solubility overviewSoluble in 0.1M NaOH (100mM)
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ImportantThis product is for RESEARCH USE ONLY and is not intended for therapeutic or diagnostic use. Not for human or veterinary use.
References for (S)-MCPG
Structure-activity relationships for a series of phenylglycine derivatives acting at metabotropic glutamate receptors (mGluRs).
Bedingfield JS et al (1995) Br J Pharmacol 116(8) : 3323-9.PubMedID: 8719814Structure-activity relationships of new agonists and antagonists of different metabotropic glutamate receptor subtypes.
Sekiyama N et al (1996) Br J Pharmacol 117(7) : 1493-503.PubMedID: 8730745Pharmacological agents acting at subtypes of metabotropic glutamate receptors.
Schoepp DD et al (1999) Neuropharmacology 38(10) : 1431-76.PubMedID: 10530808
品牌介绍
Hello Bio是由一群经验丰富的科学家和化学家们创立的充满活力的生物企业，总部位于英国布里斯托尔，在美国普林斯顿设有分公司，主旨在于提供质优价廉的生命科学研究工具，主要产品线为小分子化合物，如激动剂、拮抗剂、抑制剂等，部分产品价格甚至低至其他供应商的50%。热销产品线：酶抑制剂和激动剂ROCK inhibitor Y-27632, PKA inhibitor KT 5720 , adenylyl cyclase activator Forskolin, and novel GRK2/3 inhibitor Cmpd101等。 离子通道调节剂NMDA antagonist D-AP5, sodium channel blocker tetrodotoxin citrate, TRP antagonist capsazepine, and GABAA antagonist SR 95531 等。信号通路工具各种信号通路抑制剂、激动剂表观遗传学研究工具potent HDAC inhibitor Trichostatin A, DNA methyltransferase inhibitor 5-aza-2'-deoxycytidine,BET bromodomain inhibitor (+)-JQ1 and potent,selective GLP / G9a HMTase inhibitor BIX 01294 等受体配体novel selective GRK2/3 inhibitor, NMDA antagonist D-AP5, Group I mGlu agonist (S)-3,5-DHPG, and GABAA antagonist SR 95531.等干细胞调节剂ROCK inhibitor Y-27632, SB 431542 DAPT.
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