你好生物/（S）-MCPG/HB0056/10mg
商品编号：
HB0056-10mg
品牌：
hellobio
市场价：
¥1872.00
美元价：
1440.00
产品分类：
酸碱缓冲液
联系Q Q：
3392242852
电话号码：
4000-520-616
电子邮箱：
info@ebiomall.com
商品介绍
Productoverview
- Name(S)-MCPG
- ShortdescriptionNon-selectivegroupI/IImGluRantagoNIST
- BIOLOGicaldescription
Non-selectivegroupIandIImGluRantagonist.Watersolublesodiumsalt.
Activeenantiomerof (R,S)-MCPG.
DisplaysslightactivityatmGlu8receptorbutnoneatmGlu4receptor.InhibitsMF-LTP(mossyfiberlongtermpotentiation)andblocksinductionofLTPinCA1ofrathippocampus.
Watersoluble(R,S)-MCPGsodiumsaltand(S)-MCPGsodiumsaltalsoavailable. - Alternativenames(S)-M4CPG
- BiologicalactionAntagonist
- Purity>99%
- OurproductsinactionSubmitYourCitationNow
Properties
- Chemicalname(S)-α-Methyl-4-carboxyphenylglycine
- MolecularWeight209.2
- Chemicalstructure
![(S)-MCPG [150145-89-4]](images/hellobio/201710/hb0056.png "(S)-MCPG [150145-89-4]")
- MolecularFormulaC10H11NO4
- CASNumber150145-89-4
- PubChemidentifier446355
- SMILESC[C@](C1=CC=C(C=C1)C(=O)O)(C(=O)O)N
- SourceSynthetic
- InChiInChI=1S/C10H11NO4/c1-10(11,9(14)15)7-4-2-6(3-5-7)8(12)13/h4-5H,11H2,1H3,(H,12,13)(H,14,15)/t10-/m0/s1
- InChiKeyDNCAZYRLRMTVSF-JTQLQIEISA-N
- MDLnumberMFCD00216858
- AppearanceWhitesolid
StoringandUsingYourProduct
- StorageinstructionsRoomtemperature
- SolubilityoverviewSolublein0.1MNaOH(100mM)
- ImportantThisproductisforRESEARCHUSEONLYandisnotintendedfortherapeuticordiagnosticuse.Notforhumanorveterinaryuse.
Referencesfor(S)-MCPG
Structure-activityrelationshipsforaseriesofphenylglycinederivativesactingatmetabotropicglutamatereceptors(mGluRs).
BedingfieldJSetal(1995)BrJPharmacol116(8):3323-9.PubMedID:8719814Structure-activityrelationshipsofnewagonistsandantagonistsofdifferentmetabotropicglutamatereceptorsubtypes.
SekiyamaNetal(1996)BrJPharmacol117(7):1493-503.PubMedID:8730745Pharmacologicalagentsactingatsubtypesofmetabotropicglutamatereceptors.
SchoeppDDetal(1999)Neuropharmacology38(10):1431-76.PubMedID:10530808
品牌介绍
Hello Bio是由一群经验丰富的科学家和化学家们创立的充满活力的生物企业，总部位于英国布里斯托尔，在美国普林斯顿设有分公司，主旨在于提供质优价廉的生命科学研究工具，主要产品线为小分子化合物，如激动剂、拮抗剂、抑制剂等，部分产品价格甚至低至其他供应商的50%。热销产品线：酶抑制剂和激动剂ROCK inhibitor Y-27632, PKA inhibitor KT 5720 , adenylyl cyclase activator Forskolin, and novel GRK2/3 inhibitor Cmpd101等。 离子通道调节剂NMDA antagonist D-AP5, sodium channel blocker tetrodotoxin citrate, TRP antagonist capsazepine, and GABAA antagonist SR 95531 等。信号通路工具各种信号通路抑制剂、激动剂表观遗传学研究工具potent HDAC inhibitor Trichostatin A, DNA methyltransferase inhibitor 5-aza-2'-deoxycytidine,BET bromodomain inhibitor (+)-JQ1 and potent,selective GLP / G9a HMTase inhibitor BIX 01294 等受体配体novel selective GRK2/3 inhibitor, NMDA antagonist D-AP5, Group I mGlu agonist (S)-3,5-DHPG, and GABAA antagonist SR 95531.等干细胞调节剂ROCK inhibitor Y-27632, SB 431542 DAPT.
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