Productoverview

• Name
  (RS)-MCPG
• Shortdescription
  Non-selectivegroupIandIImGluRantagoNIST
• BIOLOGicaldescription

  Non-selectivegroupIandIImGluRantagonist.

  AlsocompetitiveantagonistofACPDsensitivereceptors.

  Showsnoeffectonlocomotoractivity.

  Watersoluble(R,S)-MCPGsodiumsaltand(S)-MCPGsodiumsaltalsoavailable.(S)-MCPGalsoavailable.

• Biologicalaction
  Antagonist
• Purity
  >98%
• Ourproductsinaction
  SubmitYourCitationNow

Properties

• Chemicalname
  (RS)-α-Methyl-4-carboxyphenylglycine
• MolecularWeight
  209.2
• Chemicalstructure
  
• MolecularFormula
  C₁₀H₁₁NO₄
• CASNumber
  146669-29-6
• PubChemidentifier
  1222
• SMILES
  CC(C1=CC=C(C=C1)C(=O)O)(C(=O)O)N
• Source
  Synthetic
• InChi
  InChI=1S/C10H11NO4/c1-10(11,9(14)15)7-4-2-6(3-5-7)8(12)13/h4-5H,11H2,1H3,(H,12,13)(H,14,15)
• InChiKey
  DNCAZYRLRMTVSF-UHFFFAOYSA-N
• MDLnumber
  MFCD00210205
• Appearance
  Whitesolid

StoringandUsingYourProduct

• Storageinstructions
  Roomtemperature
• Solubilityoverview
  Solublein0.1MNaOH(100mM)
• Important
  ThisproductisforRESEARCHUSEONLYandisnotintendedfortherapeuticordiagnosticuse.Notforhumanorveterinaryuse.

Referencesfor(RS)-MCPG

• Themetabotropicglutamatereceptorantagonist(RS)-MCPGproduceshyperlocomotioninamphetaminepre-exposedrats.

  KimJHetal(1998)Neuropharmacology37(2):189-97.

  PubMedID:9680243

• MCPGantagonizesmetabotropicglutamatereceptorsbutnotlong-termpotentiationinthehippocampus.

  ManzoniOJetal(1994)EurJNeurosci6(6):1050-4.

  PubMedID:7952274

• Competitiveantagonismatmetabotropicglutamatereceptorsby(S)-4-carboxyphenylglycineand(RS)-alpha-methyl-4-carboxyphenylglycine.

  EatonSAetal(1993)EurJPharmacol244(2):195-7.

  PubMedID:8381746