你好Bio/MCC950钠盐/HB4636/10mg
商品编号：
HB4636-10mg
品牌：
hellobio
市场价：
¥5518.50
美元价：
4245.00
产品分类：
酸碱缓冲液
联系Q Q：
3392242852
电话号码：
4000-520-616
电子邮箱：
info@ebiomall.com
商品介绍
Productoverview
- NameMCC950sodiumsalt
- ShortdescriptionPotent,selectiveNLRP3inflammasomeinhibitor
- BIOLOGicaldescriptionPotent,selectiveandorallyavailableNLRP3inflammasomeinhibitor.BlocksthereleaseofIL-1betainmacrophagesprimedwithLPSandactivatedwithATPornigericin,butitdoesnotinhibitNLRP1,NLRC4,AIM2,TLR2signalingorprimingofNLRP3.PreventsoligomerizationofASCincellsstimulatedwithLPSandnigericin.Activeinvivo,blockingtheproductionofIL-1betaandenhancingsurvivalinmousemodelsofmultiplesclerosisandcryopyrin-associatedperiodicsyndrome(CAPS).AlsoactiveinexvivosamplesfromindividualswithMuckle-Wellssyndrome.PotentialtherapeuticagentforNLRP3-associatedsyndromes,includingautoinflammatoryandautoimmunediseases.
- Purity>98%
- OurproductsinactionSubmitYourCitationNow
Properties
- Chemicalname1-(1,2,3,5,6,7-Hexahydro-s-indacen-4-yl)-3-[4-(1-hydroxy-1-methyl-ethyl)-furan-2-sulfonyl]urea
- MolecularWeight426.5
- CASNumber256373-96-3
- InChiKeySNIGCXULUAXYGW-UHFFFAOYSA-N
- AppearanceCrystallinesolid
StoringandUsingYourProduct
- Storageinstructions+4°C
- ImportantThisproductisforRESEARCHUSEONLYandisnotintendedfortherapeuticordiagnosticuse.Notforhumanorveterinaryuse.
品牌介绍
Hello Bio是由一群经验丰富的科学家和化学家们创立的充满活力的生物企业，总部位于英国布里斯托尔，在美国普林斯顿设有分公司，主旨在于提供质优价廉的生命科学研究工具，主要产品线为小分子化合物，如激动剂、拮抗剂、抑制剂等，部分产品价格甚至低至其他供应商的50%。热销产品线：酶抑制剂和激动剂ROCK inhibitor Y-27632, PKA inhibitor KT 5720 , adenylyl cyclase activator Forskolin, and novel GRK2/3 inhibitor Cmpd101等。 离子通道调节剂NMDA antagonist D-AP5, sodium channel blocker tetrodotoxin citrate, TRP antagonist capsazepine, and GABAA antagonist SR 95531 等。信号通路工具各种信号通路抑制剂、激动剂表观遗传学研究工具potent HDAC inhibitor Trichostatin A, DNA methyltransferase inhibitor 5-aza-2'-deoxycytidine,BET bromodomain inhibitor (+)-JQ1 and potent,selective GLP / G9a HMTase inhibitor BIX 01294 等受体配体novel selective GRK2/3 inhibitor, NMDA antagonist D-AP5, Group I mGlu agonist (S)-3,5-DHPG, and GABAA antagonist SR 95531.等干细胞调节剂ROCK inhibitor Y-27632, SB 431542 DAPT.
联络我们
