Hello Bio/3-Methyladenine/HB2267/100mg
商品编号：
HB2267-100mg
品牌：
hellobio
市场价：
¥1579.50
美元价：
1215.00
产品分类：
酸碱缓冲液
联系Q Q：
3392242852
电话号码：
4000-520-616
电子邮箱：
info@ebiomall.com
商品介绍
Productoverview
- Name3-Methyladenine
- ShortdescriptionPI-3Kinhibitor
- BIOLOGicaldescriptionPhosphoinositide3-kinase(PI-3K)inhibitor.Inhibitsautophagy,modulatesendosomalmembranetraffickingandstimulatesADIpocytePKA-dependentlipolysis.Maypotentiatetheactionofanticancerdrugs.
- BiologicalactionInhibitor
- Purity>99%
- OurproductsinactionSubmitYourCitationNow
Properties
- Chemicalname3-Methyl-3H-purin-6-amine
- MolecularWeight149.15
- MolecularFormulaC6H7N5
- CASNumber5142-23-4
StoringandUsingYourProduct
- Storageinstructions+4°C
- ImportantThisproductisforRESEARCHUSEONLYandisnotintendedfortherapeuticordiagnosticuse.Notforhumanorveterinaryuse.
Referencesfor3-Methyladenine
3-Methyladenine,aninhibitorofautophagy,hasmultipleeffectsonmetabolism.
Caroetal(1988)EurJBiochem175(2):325-9PubMedID:34024593-Methyladenineinducescelldeathanditsinteractionwithchemotherapeuticdrugsisindependentofautophagy.
Shengetal(2013)BiochemBiophysResCommun.432(1):5-9PubMedID:233956793-Methyladeninespecificallyinhibitsretrogradetransportofcation-independentmannose6-phosphate/insulin-likegrowthfactorIIreceptorfromtheearlyendosometotheTGN.
Hirosakoetal(2004)BiochemBiophysResCommun316(3):845-52PubMedID:15033478
品牌介绍
Hello Bio是由一群经验丰富的科学家和化学家们创立的充满活力的生物企业，总部位于英国布里斯托尔，在美国普林斯顿设有分公司，主旨在于提供质优价廉的生命科学研究工具，主要产品线为小分子化合物，如激动剂、拮抗剂、抑制剂等，部分产品价格甚至低至其他供应商的50%。热销产品线：酶抑制剂和激动剂ROCK inhibitor Y-27632, PKA inhibitor KT 5720 , adenylyl cyclase activator Forskolin, and novel GRK2/3 inhibitor Cmpd101等。 离子通道调节剂NMDA antagonist D-AP5, sodium channel blocker tetrodotoxin citrate, TRP antagonist capsazepine, and GABAA antagonist SR 95531 等。信号通路工具各种信号通路抑制剂、激动剂表观遗传学研究工具potent HDAC inhibitor Trichostatin A, DNA methyltransferase inhibitor 5-aza-2'-deoxycytidine,BET bromodomain inhibitor (+)-JQ1 and potent,selective GLP / G9a HMTase inhibitor BIX 01294 等受体配体novel selective GRK2/3 inhibitor, NMDA antagonist D-AP5, Group I mGlu agonist (S)-3,5-DHPG, and GABAA antagonist SR 95531.等干细胞调节剂ROCK inhibitor Y-27632, SB 431542 DAPT.
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