Hello Bio/3-Methyladenine/HB2267/50mg
商品编号：
HB2267-50mg
品牌：
hellobio
市场价：
¥1111.50
美元价：
855.00
产品分类：
酸碱缓冲液
联系Q Q：
3392242852
电话号码：
4000-520-616
电子邮箱：
info@ebiomall.com
商品介绍
Product overview
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Name3-Methyladenine
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Short descriptionPI-3K inhibitor
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Biological descriptionPhosphoinositide 3-kinase (PI-3K) inhibitor. Inhibits autophagy, modulates endosomal membrane trafficking and stimulates adipocyte PKA-dependent lipolysis. May potentiate the action of anticancer drugs.
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Biological actionInhibitor
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Purity>99%
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Properties
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Chemical name3-Methyl-3H-purin-6-amine
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Molecular Weight149.15
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Molecular FormulaC6H7N5
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CAS Number5142-23-4
Storing and Using Your Product
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Storage instructions+4°C
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ImportantThis product is for RESEARCH USE ONLY and is not intended for therapeutic or diagnostic use. Not for human or veterinary use.
References for 3-Methyladenine
3-Methyladenine, an inhibitor of autophagy, has multiple effects on metabolism.
Caro et al (1988) Eur J Biochem 175(2) : 325-9PubMedID: 34024593-Methyladenine induces cell death and its interaction with chemotherapeutic drugs is independent of autophagy.
Sheng et al (2013) Biochem Biophys Res Commun. 432(1) : 5-9PubMedID: 233956793-Methyladenine specifically inhibits retrograde transport of cation-independent mannose 6-phosphate/insulin-like growth factor II receptor from the early endosome to the TGN.
Hirosako et al (2004) Biochem Biophys Res Commun 316(3) : 845-52PubMedID: 15033478
品牌介绍
Hello Bio是由一群经验丰富的科学家和化学家们创立的充满活力的生物企业，总部位于英国布里斯托尔，在美国普林斯顿设有分公司，主旨在于提供质优价廉的生命科学研究工具，主要产品线为小分子化合物，如激动剂、拮抗剂、抑制剂等，部分产品价格甚至低至其他供应商的50%。热销产品线：酶抑制剂和激动剂ROCK inhibitor Y-27632, PKA inhibitor KT 5720 , adenylyl cyclase activator Forskolin, and novel GRK2/3 inhibitor Cmpd101等。 离子通道调节剂NMDA antagonist D-AP5, sodium channel blocker tetrodotoxin citrate, TRP antagonist capsazepine, and GABAA antagonist SR 95531 等。信号通路工具各种信号通路抑制剂、激动剂表观遗传学研究工具potent HDAC inhibitor Trichostatin A, DNA methyltransferase inhibitor 5-aza-2'-deoxycytidine,BET bromodomain inhibitor (+)-JQ1 and potent,selective GLP / G9a HMTase inhibitor BIX 01294 等受体配体novel selective GRK2/3 inhibitor, NMDA antagonist D-AP5, Group I mGlu agonist (S)-3,5-DHPG, and GABAA antagonist SR 95531.等干细胞调节剂ROCK inhibitor Y-27632, SB 431542 DAPT.
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