Hello Bio/Lonidamine/HB0993/50mg
商品编号：
HB0993-50mg
品牌：
hellobio
市场价：
¥4992.00
美元价：
3840.00
产品分类：
酸碱缓冲液
联系Q Q：
3392242852
电话号码：
4000-520-616
电子邮箱：
info@ebiomall.com
商品介绍
Productoverview
- NameLonidamine
- ShortdescriptionMitochondrialhexokinaseinhibitor
- BIOLOGicaldescriptionMitochondrialhexokinaseinhibitor;inhibitsglycolysis.BlocksCFTRchannelcurrents(Kd=58µM).Showsantispermatogenicandantitumoractions.
- BiologicalactionInhibitor
- Purity>98%
- OurproductsinactionSubmitYourCitationNow
Properties
- Chemicalname1-[(2,4-Dichlorophenyl)methyl]-1H-indazole-3-carboxylicacid
- MolecularWeight321.16
- Chemicalstructure
![Lonidamine [50264-69-2]](images/hellobio/201710/hb0993.png "Lonidamine [50264-69-2]")
- MolecularFormulaC15H10Cl2N2O2
- CASNumber50264-69-2
StoringandUsingYourProduct
- Storageinstructionsroomtemperature
- Solubilityoverviewsolubleinethanol(5mM)orDMSO(100mM)
- ImportantThisproductisforRESEARCHUSEONLYandisnotintendedfortherapeuticordiagnosticuse.Notforhumanorveterinaryuse.
ReferencesforLonidamine
MechanismoflonidamineinhibitionoftheCFTRchloridechannel.
GongXetal(2002)BrJPharmacol137(6):928-36.PubMedID:12411425Lonidamine:basicscienceandrationalefortreatmentofprostaticproliferativedisorders.
BrawerMK(2005)RevUrol7Suppl7:S21-6.PubMedID:16986057Recentstudiesonlonidamine,theleadcompoundoftheantispermatogenicindazol-carboxylicacids.
GattoMTetal(2002)Contraception65(4):277-8.PubMedID:12020777
品牌介绍
Hello Bio是由一群经验丰富的科学家和化学家们创立的充满活力的生物企业，总部位于英国布里斯托尔，在美国普林斯顿设有分公司，主旨在于提供质优价廉的生命科学研究工具，主要产品线为小分子化合物，如激动剂、拮抗剂、抑制剂等，部分产品价格甚至低至其他供应商的50%。热销产品线：酶抑制剂和激动剂ROCK inhibitor Y-27632, PKA inhibitor KT 5720 , adenylyl cyclase activator Forskolin, and novel GRK2/3 inhibitor Cmpd101等。 离子通道调节剂NMDA antagonist D-AP5, sodium channel blocker tetrodotoxin citrate, TRP antagonist capsazepine, and GABAA antagonist SR 95531 等。信号通路工具各种信号通路抑制剂、激动剂表观遗传学研究工具potent HDAC inhibitor Trichostatin A, DNA methyltransferase inhibitor 5-aza-2'-deoxycytidine,BET bromodomain inhibitor (+)-JQ1 and potent,selective GLP / G9a HMTase inhibitor BIX 01294 等受体配体novel selective GRK2/3 inhibitor, NMDA antagonist D-AP5, Group I mGlu agonist (S)-3,5-DHPG, and GABAA antagonist SR 95531.等干细胞调节剂ROCK inhibitor Y-27632, SB 431542 DAPT.
联络我们
