Hello Bio/Lavendustin C/HB0376/50mg
商品编号：
HB0376-50mg
品牌：
hellobio
市场价：
¥10530.00
美元价：
8100.00
产品分类：
酸碱缓冲液
联系Q Q：
3392242852
电话号码：
4000-520-616
电子邮箱：
info@ebiomall.com
商品介绍
Productoverview
- NameLavendustinC
- ShortdescriptionPotentEGFRtyrosinekinaseinhibitor
- BIOLOGicaldescriptionPotentEGFreceptortyrosinekinase(IC50=11nM)andc-src(IC50=500nM)inhibitor.InhibitsCa2+/calmodulinkinaseII(IC50=200nM).BlocksLTPinduction.
- BiologicalactionInhibitor
- Purity>98%
- OurproductsinactionSubmitYourCitationNow
Properties
- Chemicalname5-((2,5-Dihydroxybenzyl)amino)-2-hydroxybenzoicacid
- MolecularWeight275.3
- Chemicalstructure
![Lavendustin C [125697-93-0]](images/hellobio/201710/hb0376.png "Lavendustin C [125697-93-0]")
- MolecularFormulaC14H13NO5
- CASNumber125697-93-0
- PubChemidentifier3896
- SMILESC1=CC(=C(C=C1NCC2=C(C=CC(=C2)O)O)C(=O)O)O
StoringandUsingYourProduct
- SolubilityoverviewsolubleinDMSOormethanol
- ImportantThisproductisforRESEARCHUSEONLYandisnotintendedfortherapeuticordiagnosticuse.Notforhumanorveterinaryuse.
ReferencesforLavendustinC
Isolationofanoveltyrosinekinaseinhibitor,lavendustinA,fromStreptomycesgriseolavendus.
OnodaTetal(1989)JNatProd52(6):1252-7.PubMedID:2614420Long-termpotentiationinthehippocampusisblockedbytyrosinekinaseinhibitors.
O"DellTJetal(1991)Nature353(6344):558-60.PubMedID:1656271InvolvementofCa2+/calmodulin-dependentproteinkinaseIIinendothelialNOproductionandendothelium-dependentrelaxation.
SchneiderJCetal(2003)AmJPhysiolHeartCircPhysiol284(6):H2311-9.PubMedID:12560211Roleofthemitogen-activatedproteinkinasesandtyrosinekinasesduringleukotrieneB4-inducedeosinophilactivation.
LindsayMAetal(1998)JLeukocBiol64(4):555-62.PubMedID:9766637
品牌介绍
Hello Bio是由一群经验丰富的科学家和化学家们创立的充满活力的生物企业，总部位于英国布里斯托尔，在美国普林斯顿设有分公司，主旨在于提供质优价廉的生命科学研究工具，主要产品线为小分子化合物，如激动剂、拮抗剂、抑制剂等，部分产品价格甚至低至其他供应商的50%。热销产品线：酶抑制剂和激动剂ROCK inhibitor Y-27632, PKA inhibitor KT 5720 , adenylyl cyclase activator Forskolin, and novel GRK2/3 inhibitor Cmpd101等。 离子通道调节剂NMDA antagonist D-AP5, sodium channel blocker tetrodotoxin citrate, TRP antagonist capsazepine, and GABAA antagonist SR 95531 等。信号通路工具各种信号通路抑制剂、激动剂表观遗传学研究工具potent HDAC inhibitor Trichostatin A, DNA methyltransferase inhibitor 5-aza-2'-deoxycytidine,BET bromodomain inhibitor (+)-JQ1 and potent,selective GLP / G9a HMTase inhibitor BIX 01294 等受体配体novel selective GRK2/3 inhibitor, NMDA antagonist D-AP5, Group I mGlu agonist (S)-3,5-DHPG, and GABAA antagonist SR 95531.等干细胞调节剂ROCK inhibitor Y-27632, SB 431542 DAPT.
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