Hello Bio/Lavendustin C/HB0376/10mg
商品编号：
HB0376-10mg
品牌：
hellobio
市场价：
¥2535.00
美元价：
1950.00
产品分类：
酸碱缓冲液
联系Q Q：
3392242852
电话号码：
4000-520-616
电子邮箱：
info@ebiomall.com
商品介绍
Product overview
-
NameLavendustin C
-
Short descriptionPotent EGFR tyrosine kinase inhibitor
-
Biological descriptionPotent EGF receptor tyrosine kinase (IC50 = 11 nM) and c-src (IC50 = 500 nM) inhibitor. Inhibits Ca2+/calmodulin kinase II (IC50 = 200 nM). Blocks LTP induction.
-
Biological actionInhibitor
-
Purity>98%
-
Our products in actionSubmit Your Citation Now
Properties
-
Chemical name5-((2,5-Dihydroxybenzyl)amino)-2-hydroxybenzoic acid
-
Molecular Weight275.3
-
Chemical structure
![Lavendustin C [125697-93-0]](images/hellobio/201710/hb0376.png "Lavendustin C [125697-93-0]")
-
Molecular FormulaC14H13NO5
-
CAS Number125697-93-0
-
PubChem identifier3896
-
SMILESC1=CC(=C(C=C1NCC2=C(C=CC(=C2)O)O)C(=O)O)O
Storing and Using Your Product
-
Solubility overviewsoluble in DMSO or methanol
-
ImportantThis product is for RESEARCH USE ONLY and is not intended for therapeutic or diagnostic use. Not for human or veterinary use.
References for Lavendustin C
Isolation of a novel tyrosine kinase inhibitor, lavendustin A, from Streptomyces griseolavendus.
Onoda T et al (1989) J Nat Prod 52(6) : 1252-7.PubMedID: 2614420Long-term potentiation in the hippocampus is blocked by tyrosine kinase inhibitors.
O'Dell TJ et al (1991) Nature 353(6344) : 558-60.PubMedID: 1656271Involvement of Ca2+/calmodulin-dependent protein kinase II in endothelial NO production and endothelium-dependent relaxation.
Schneider JC et al (2003) Am J Physiol Heart Circ Physiol 284(6) : H2311-9.PubMedID: 12560211Role of the mitogen-activated protein kinases and tyrosine kinases during leukotriene B4-induced eosinophil activation.
Lindsay MA et al (1998) J Leukoc Biol 64(4) : 555-62.PubMedID: 9766637
品牌介绍
Hello Bio是由一群经验丰富的科学家和化学家们创立的充满活力的生物企业，总部位于英国布里斯托尔，在美国普林斯顿设有分公司，主旨在于提供质优价廉的生命科学研究工具，主要产品线为小分子化合物，如激动剂、拮抗剂、抑制剂等，部分产品价格甚至低至其他供应商的50%。热销产品线：酶抑制剂和激动剂ROCK inhibitor Y-27632, PKA inhibitor KT 5720 , adenylyl cyclase activator Forskolin, and novel GRK2/3 inhibitor Cmpd101等。 离子通道调节剂NMDA antagonist D-AP5, sodium channel blocker tetrodotoxin citrate, TRP antagonist capsazepine, and GABAA antagonist SR 95531 等。信号通路工具各种信号通路抑制剂、激动剂表观遗传学研究工具potent HDAC inhibitor Trichostatin A, DNA methyltransferase inhibitor 5-aza-2'-deoxycytidine,BET bromodomain inhibitor (+)-JQ1 and potent,selective GLP / G9a HMTase inhibitor BIX 01294 等受体配体novel selective GRK2/3 inhibitor, NMDA antagonist D-AP5, Group I mGlu agonist (S)-3,5-DHPG, and GABAA antagonist SR 95531.等干细胞调节剂ROCK inhibitor Y-27632, SB 431542 DAPT.
联络我们
