Hello Bio/Latrunculin A/HB0375/500μg
商品编号：
HB0375-500μg
品牌：
hellobio
市场价：
¥5518.50
美元价：
4245.00
产品分类：
酸碱缓冲液
联系Q Q：
3392242852
电话号码：
4000-520-616
电子邮箱：
info@ebiomall.com
商品介绍
Product overview
-
NameLatrunculin A
-
Short descriptionActin polymerization inhibitor
-
Biological descriptionActin polymerization inhibitor that binds to monomeric G actin (Kd = 0.2 µM). Also inhibits adenine nucleotide exchange on actin. Plays a role in depolymerization of tumor cell cytoskeleton and shows possible anti-inflammatory properties.
-
Biological actionInhibitor
-
Purity>96%
-
Our products in actionSubmit Your Citation Now
Properties
-
Chemical name4-[(1R,4Z,8E,10Z,12S,15R, 17R)-17-Hydroxy-5,12-dimethyl-3-oxo -2,16-dioxabicyclo[13.3.1]nonadeca-4,8,10-trien-17 -yl)-2-thiazolidinone
-
Molecular Weight421.55
-
Chemical structure
![Latrunculin A [76343-93-6]](images/hellobio/201710/hb0375.png "Latrunculin A [76343-93-6]")
-
Molecular FormulaC22H31NO5S
-
CAS Number76343-93-6
-
PubChem identifier445420
-
SMILESC[C@H]/1CC[C@@H]2C[C@H](C[C@@](O2)([C@@H]3CSC(=O)N3)O)OC(=O)/C=C(CC/C=C/C=C1)/C
-
InChiInChI=1S/C22H31NO5S/c1-15-7-5-3-4-6-8-16(2)11-20(24)27-18-12-17(10-9-15)28-22(26,13-18)19-14-29-21(25)23-19/h3-5,7,11,15,17-19,26H,6,8-10,12-14H2,1-2H3,(H,23,25)/b4-3+,7-5-,16-11-/t15-,17-,18-,19+,22-/m1/s1
-
InChiKeyDDVBPZROPPMBLW-IZGXTMSKSA-N
Storing and Using Your Product
-
Storage instructions-20°C
-
Solubility overviewSoluble in DMSO (10mM)
-
ImportantThis product is for RESEARCH USE ONLY and is not intended for therapeutic or diagnostic use. Not for human or veterinary use.
References for Latrunculin A
Actin-latrunculin A structure and function. Differential modulation of actin-binding protein function by latrunculin A.
Yarmola EG et al (2000) J Biol Chem 275(36) : 28120-7.PubMedID: 10859320Characterization of the activities of actin-affecting drugs on tumor cell migration.
Hayot C et al (2006) Toxicol Appl Pharmacol 211(1) : 30-40.PubMedID: 16005926Inhibition of actin polymerization by latrunculin A.
Coué M et al (1987) FEBS Lett 213(2) : 316-8.PubMedID: 3556584
品牌介绍
Hello Bio是由一群经验丰富的科学家和化学家们创立的充满活力的生物企业，总部位于英国布里斯托尔，在美国普林斯顿设有分公司，主旨在于提供质优价廉的生命科学研究工具，主要产品线为小分子化合物，如激动剂、拮抗剂、抑制剂等，部分产品价格甚至低至其他供应商的50%。热销产品线：酶抑制剂和激动剂ROCK inhibitor Y-27632, PKA inhibitor KT 5720 , adenylyl cyclase activator Forskolin, and novel GRK2/3 inhibitor Cmpd101等。 离子通道调节剂NMDA antagonist D-AP5, sodium channel blocker tetrodotoxin citrate, TRP antagonist capsazepine, and GABAA antagonist SR 95531 等。信号通路工具各种信号通路抑制剂、激动剂表观遗传学研究工具potent HDAC inhibitor Trichostatin A, DNA methyltransferase inhibitor 5-aza-2'-deoxycytidine,BET bromodomain inhibitor (+)-JQ1 and potent,selective GLP / G9a HMTase inhibitor BIX 01294 等受体配体novel selective GRK2/3 inhibitor, NMDA antagonist D-AP5, Group I mGlu agonist (S)-3,5-DHPG, and GABAA antagonist SR 95531.等干细胞调节剂ROCK inhibitor Y-27632, SB 431542 DAPT.
联络我们
